UNSPECIFIED (2003) Changing socioeconomic risk factors for invasive H-influenzae disease after the introduction of conjugate vaccine. JOURNAL OF INFECTION, 46 (1). pp. 46-48. doi:10.1053/jinf.2002.1069 ISSN 0163-4453.

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Abstract

Objectives: To determine socioeconomic risk factors for invasive Haemophilus influenzae (HI) disease before and after the introduction of HI type b (Hib) conjugate vaccine in the West Midlands, UK.

Methods. Study population consisted of children aged <5 years with laboratory confirmed invasive disease. Linear associations between disease rates and socioeconomic variables were examined 2-years before and 2-years after the introduction of conjugate vaccine.

Results: Pre-vaccine there were no trends in disease incidence. Post-vaccine there was an absolute reduction in disease incidence and significant disease differentials between affluent and deprived populations were identified for non-owner-occupancy (P = 0.032) and car access (P = 0.049).

Conclusions: Our results suggest that changes in socioeconomic risk factor for invasive HI occurred after the introduction of conjugate vaccine. This may have implications for future immunisation strategies. (C) 2002 The British Infection Society. Published by Elsevier Science Ltd. All rights reserved.

Item Type:	Journal Article
Subjects:	Q Science > QR Microbiology > QR355 Virology
Journal or Publication Title:	JOURNAL OF INFECTION
Publisher:	W B SAUNDERS CO LTD
ISSN:	0163-4453
Official Date:	January 2003
Dates:	Date Event January 2003 UNSPECIFIED
Volume:	46
Number:	1
Number of Pages:	3
Page Range:	pp. 46-48
DOI:	10.1053/jinf.2002.1069
Publication Status:	Published

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