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Preventing vitamin D deficiency (VDD) : a systematic review of economic evaluations

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Aguiar, M., Andronis, L. (Lazaros) , Pallan, M., Hogler, W. and Frew, E. (2017) Preventing vitamin D deficiency (VDD) : a systematic review of economic evaluations. European Journal of Public Health, 27 (2). pp. 292-301. doi:10.1093/eurpub/ckw270 ISSN 1101-1262.

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Official URL: https://doi.org/10.1093/eurpub/ckw270

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Abstract

Background: Vitamin D deficiency (VDD) is a public health concern worldwide. If untreated, it can lead to reduced quality of life and escalated costs brought about by ill-health. Preventive programmes to improve population vitamin D status exist but little is known about their cost-effectiveness. This information is vital so that decision-makers adopt efficient strategies and optimise use of public resources. Aims: Systematically review and critically appraise economic evaluations of population strategies to prevent VDD. Methods: The databases reviewed were MEDLINE, EMBASE, Econlit, NHS EED, CEA, and RepEc. All full economic evaluations of VDD prevention strategies were included. Interventions considered were food fortification, supplementation and public health campaigns. Data extracted included type of evaluation, population, setting, measure of benefit and main results. Results: Of the 2492 records screened, 14 studies were included. The majority of studies focused on supplementation within at-risk groups with the primary objective of either preventing fractures or falls in older adults. There was insufficient economic evidence to draw conclusions about the cost-effectiveness of population strategies. No study was identified that offered a direct comparison of the two main alternative population strategies: food fortification vs. supplementation. Conclusions: Whilst there is a growing body of evidence on the cost-effectiveness of micro nutrient programmes, there is a paucity of data on vitamin D fortification and how fortification programmes compare to population supplementation programmes. We highlight research gaps, and offer suggestions of what is required to undertake population-based cost-effectiveness analysis.

Item Type: Journal Article
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Journal or Publication Title: European Journal of Public Health
Publisher: Oxford University Press
ISSN: 1101-1262
Official Date: 1 April 2017
Dates:
DateEvent
1 April 2017Published
15 February 2017Available
Volume: 27
Number: 2
Page Range: pp. 292-301
DOI: 10.1093/eurpub/ckw270
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access

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