The Library
c-MYC: More than just a matter of life and death
Tools
Tools
Tools
UNSPECIFIED (2002) c-MYC: More than just a matter of life and death. Nature, 2 (10). pp. 764-776. ISSN 1474-175X
Full text not available from this repository.
Official URL: http://dx.doi.org/10.1038/nrc904
Abstract
Deregulated expression of c-MYC occurs in a broad range of human cancers and is often associated with poor prognosis, indicating a key role for this oncogene in tumour progression. However, as established human tumours often bear multiple genetic lesions, it is difficult to determine whether c-MYC is instrumental in the initiation/progression of the tumour, or indeed whether inactivating c-MYC would lead to tumour regression. Regulatable transgenic mouse models of oncogenesis have shed light on these issues and provide hope for effective cancer therapies.
| Item Type: | Journal Item | ||||
|---|---|---|---|---|---|
| Subjects: | R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) | ||||
| Journal or Publication Title: | Nature | ||||
| Publisher: | NATURE PUBLISHING GROUP | ||||
| ISSN: | 1474-175X | ||||
| Official Date: | October 2002 | ||||
| Dates: |
|
||||
| Volume: | 2 | ||||
| Number: | 10 | ||||
| Number of Pages: | 13 | ||||
| Page Range: | pp. 764-776 | ||||
| Identification Number: | 10.1038/nrc904 | ||||
| Publication Status: | Published | ||||
| URI: | http://wrap.warwick.ac.uk/id/eprint/10126 |
Data sourced from Thomson Reuters' Web of Knowledge
Request changes or add full text files to a record
Actions (login required)
 |
View Item |
