Skip to content Skip to navigation
University of Warwick
  • Study
  • |
  • Research
  • |
  • Business
  • |
  • Alumni
  • |
  • News
  • |
  • About

University of Warwick
Publications service & WRAP

Highlight your research

  • WRAP
    • Home
    • Search WRAP
    • Browse by Warwick Author
    • Browse WRAP by Year
    • Browse WRAP by Subject
    • Browse WRAP by Department
    • Browse WRAP by Funder
    • Browse Theses by Department
  • Publications Service
    • Home
    • Search Publications Service
    • Browse by Warwick Author
    • Browse Publications service by Year
    • Browse Publications service by Subject
    • Browse Publications service by Department
    • Browse Publications service by Funder
  • Help & Advice
University of Warwick

The Library

  • Login
  • Admin

Effect of maternal HIV status on vaccination coverage among sub-Saharan African children : a socio-ecological analysis

Tools
- Tools
+ Tools

Adetokunboh, Olatunji O., Uthman, Olalekan A. and Wiysonge, Charles S. (2018) Effect of maternal HIV status on vaccination coverage among sub-Saharan African children : a socio-ecological analysis. Human Vaccines & Immunotherapeutics, 14 (10). pp. 2373-2381. doi:10.1080/21645515.2018.1467204 ISSN 2164-554X.

[img]
Preview
PDF
WRAP-effect-maternal-HIV-status-Saharan-African-children-analysis-Uthman-2018.pdf - Published Version - Requires a PDF viewer.
Available under License Creative Commons Attribution Non-commercial No Derivatives 4.0.

Download (1616Kb) | Preview
[img] PDF
WRAP-effect-maternal-HIV-status-vaccination-coverage-among-sub-Saharan-African-children-Uthman-2018.pdf - Accepted Version
Embargoed item. Restricted access to Repository staff only - Requires a PDF viewer.

Download (1013Kb)
Official URL: https://doi.org/10.1080/21645515.2018.1467204

Request Changes to record.

Abstract

We investigated the relationship between maternal HIV status and uptake of the full series of three doses of diphtheria-tetanus-pertussis containing vaccines (DTP3) in sub-Saharan African children. We used data obtained from demographic and health surveys conducted in sub-Saharan Africa. We conducted meta-analysis and calculated pooled odds ratios (OR) for the association between maternal HIV status and DTP3 vaccination status for each country. A total of 4,187 out of 5,537 children of women living with HIV received DTP3 (75.6%), compared to 71,290 of 113,513 (62.8%) children of HIV negative women. National DTP3 coverage among children of HIV-positive women varied between 24% and 96% while among children of HIV negative women it was between 26% and 92%. Overall pooled result showed no significant difference in DTP3 coverage between the two groups (OR = 1.05; 95% confidence interval 0.91 - 1.22), with statistically significant heterogeneity (Chi2 = 91.63, P = 0.000, I2 = 71.6%). There was no significant association between DTP3 coverage and maternal HIV status in sub-Saharan Africa. However, DTP3 coverage for both HIV-exposed and non-exposed children were below the required target. Meta-regression revealed no significant association between DTP3 coverage and country characteristics (e.g. HIV prevalence among women, antiretroviral therapy coverage, gross domestic product per capita, human development index, adult literacy rate and sub-region). Improved prevention of mother-to-child transmission services might have contributed to some extent to the higher DTP3 vaccination coverage among the HIV-exposed children. There is also need to address barriers impeding uptake of vaccination among HIV-exposed and non-exposed children.

Item Type: Journal Article
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Population, Evidence & Technologies (PET)
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Diphtheria -- Vaccination -- Africa, Tetanus -- Vaccination -- Africa, Whooping cough -- Vaccination -- Africa, HIV-positive women -- Africa
Journal or Publication Title: Human Vaccines & Immunotherapeutics
Publisher: Taylor & Francis Inc.
ISSN: 2164-554X
Official Date: 22 May 2018
Dates:
DateEvent
22 May 2018Published
2 May 2018Available
3 April 2018Accepted
Volume: 14
Number: 10
Page Range: pp. 2373-2381
DOI: 10.1080/21645515.2018.1467204
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access (Creative Commons)
Date of first compliant deposit: 19 April 2018
Date of first compliant Open Access: 31 May 2018
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
106035National Research Foundationhttp://dx.doi.org/10.13039/501100001321
112800National Research Foundationhttp://dx.doi.org/10.13039/501100001321
UNSPECIFIEDNational Institute for Health Researchhttp://dx.doi.org/10.13039/501100000272
Related URLs:
  • Publisher

Request changes or add full text files to a record

Repository staff actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics

twitter

Email us: wrap@warwick.ac.uk
Contact Details
About Us