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Expressed emotion as a predictor of the first psychotic episode - Results of the European prediction of psychosis study
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Haidl, Theresa, Rosen, Marlene, Schultze-Lutter, Frauke, Nieman, Dorien, Eggers, Susanne, Heinimaa, Markus, Juckel, Georg, Heinz, Andreas, Morrison, Anthony, Linszen, Don, Salokangas, Raimo, Klosterkötter, Joachim, Birchwood, Max, Patterson, Paul and Ruhrmann, Stephan (2018) Expressed emotion as a predictor of the first psychotic episode - Results of the European prediction of psychosis study. Schizophrenia Research, 199 . pp. 346-352. doi:10.1016/j.schres.2018.03.019 ISSN 0920-9964.
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Official URL: https://doi.org/10.1016/j.schres.2018.03.019
Abstract
To investigate the impact of expressed emotion (EE) on the risk of developing the first psychotic episode (FEP). The European Prediction of Psychosis Study (EPOS) investigated 245 patients who were at clinical high risk (CHR) of psychosis. The predictive value of EE alone and as a part of the multivariate EPOS model was evaluated. "Perceived irritability", a domain of the Level of Expressed Emotion Scale (LEE), was found to be predictive for the First Psychotic Episode (FEP), even as an individual variable. Furthermore, it was selected in the multivariate EPOS prediction model, thereby replacing two of the original predictor variables. This led to an improved revised version that enabled the identification of three significantly different risk classes with a hazard rate of up to 0.911. CHR subjects who perceive the most important person in their individual social environment to be limited in their stress coping skills had a higher risk of conversion to the first psychotic episode. The importance of this risk factor was further demonstrated by an improvement of risk estimation in the original EPOS predictor model. Perceiving a reference person as stress-prone and thus potentially unreliable might amplify self-experienced uncertainty and anxiety, which are often associated with the prodromal phase. Such an enforcement of stress-related processes could promote a conversion to psychosis. [Abstract copyright: Copyright © 2018 Elsevier B.V. All rights reserved.]
Item Type: | Journal Article | |||||||||
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Subjects: | R Medicine > RC Internal medicine | |||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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SWORD Depositor: | Library Publications Router | |||||||||
Library of Congress Subject Headings (LCSH): | Psychoses -- Physiological aspects -- Research, Schizophrenics, Expression, Psychotherapy | |||||||||
Journal or Publication Title: | Schizophrenia Research | |||||||||
Publisher: | Elsevier BV | |||||||||
ISSN: | 0920-9964 | |||||||||
Official Date: | September 2018 | |||||||||
Dates: |
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Volume: | 199 | |||||||||
Page Range: | pp. 346-352 | |||||||||
DOI: | 10.1016/j.schres.2018.03.019 | |||||||||
Status: | Peer Reviewed | |||||||||
Publication Status: | Published | |||||||||
Access rights to Published version: | Restricted or Subscription Access | |||||||||
Date of first compliant deposit: | 17 July 2019 | |||||||||
Date of first compliant Open Access: | 17 July 2019 | |||||||||
RIOXX Funder/Project Grant: |
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