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Expressed emotion as a predictor of the first psychotic episode - Results of the European prediction of psychosis study

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Haidl, Theresa, Rosen, Marlene, Schultze-Lutter, Frauke, Nieman, Dorien, Eggers, Susanne, Heinimaa, Markus, Juckel, Georg, Heinz, Andreas, Morrison, Anthony, Linszen, Don, Salokangas, Raimo, Klosterkötter, Joachim, Birchwood, Max, Patterson, Paul and Ruhrmann, Stephan (2018) Expressed emotion as a predictor of the first psychotic episode - Results of the European prediction of psychosis study. Schizophrenia Research, 199 . pp. 346-352. doi:10.1016/j.schres.2018.03.019 ISSN 0920-9964.

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Official URL: https://doi.org/10.1016/j.schres.2018.03.019

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Abstract

To investigate the impact of expressed emotion (EE) on the risk of developing the first psychotic episode (FEP). The European Prediction of Psychosis Study (EPOS) investigated 245 patients who were at clinical high risk (CHR) of psychosis. The predictive value of EE alone and as a part of the multivariate EPOS model was evaluated. "Perceived irritability", a domain of the Level of Expressed Emotion Scale (LEE), was found to be predictive for the First Psychotic Episode (FEP), even as an individual variable. Furthermore, it was selected in the multivariate EPOS prediction model, thereby replacing two of the original predictor variables. This led to an improved revised version that enabled the identification of three significantly different risk classes with a hazard rate of up to 0.911. CHR subjects who perceive the most important person in their individual social environment to be limited in their stress coping skills had a higher risk of conversion to the first psychotic episode. The importance of this risk factor was further demonstrated by an improvement of risk estimation in the original EPOS predictor model. Perceiving a reference person as stress-prone and thus potentially unreliable might amplify self-experienced uncertainty and anxiety, which are often associated with the prodromal phase. Such an enforcement of stress-related processes could promote a conversion to psychosis. [Abstract copyright: Copyright © 2018 Elsevier B.V. All rights reserved.]

Item Type: Journal Article
Subjects: R Medicine > RC Internal medicine
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
SWORD Depositor: Library Publications Router
Library of Congress Subject Headings (LCSH): Psychoses -- Physiological aspects -- Research, Schizophrenics, Expression, Psychotherapy
Journal or Publication Title: Schizophrenia Research
Publisher: Elsevier BV
ISSN: 0920-9964
Official Date: September 2018
Dates:
DateEvent
September 2018Published
13 April 2018Available
12 March 2018Accepted
Volume: 199
Page Range: pp. 346-352
DOI: 10.1016/j.schres.2018.03.019
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Date of first compliant deposit: 17 July 2019
Date of first compliant Open Access: 17 July 2019
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
QLG4-CT-2001-01081 Fifth Framework Programmehttp://dx.doi.org/10.13039/100011104
UNSPECIFIEDCollaboration for Leadership in Applied Health Research and Care West MidlandsUNSPECIFIED

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