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Data for Millennia of genomic stability within the invasive Para C Lineage of Salmonella enterica: ParaC genome SNPs 2
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Zhou, Zhemin, Lundstrøm, Inge, Dien, Alicia Tran, Duchêne, Sebastián, Alikhan, Nabil-Fareed, Sergeant, Martin J., Langridge, Gemma, Fotakis, Anna K., Nair, Satheesh, Stenøien, Hans K., Hamre, Stian S., Casjens, Sherwood, Quince, Christopher , Christophersen, Axel, Thomson, Nicholas R., Weill, François-Xavier, Ho, Simon, Gilbert, M. Thomas P. and Achtman, Mark (2018) Data for Millennia of genomic stability within the invasive Para C Lineage of Salmonella enterica: ParaC genome SNPs 2. [Dataset]
![[img]](https://wrap.warwick.ac.uk/style/images/fileicons/application_vnd.ms-excel.png) |
Microsoft Excel (SNPs in the core genome of the Para C Lineage plus Birkenhead.)
ParaC genome SNPs 2.xlsx - Published Version Available under License Creative Commons Attribution 4.0. Download (41Mb) |
Official URL: http://wrap.warwick.ac.uk/101832/
Abstract
Salmonella enterica serovar Paratyphi C is the causative agent of enteric (paratyphoid) fever. While today a potentially lethal infection of humans that occurs in Africa and Asia, early 20th century observations in Eastern Europe suggest it may once have had a wider-ranging impact on human societies. We recovered a draft Paratyphi C genome from the 800-year-old skeleton of a young woman in Trondheim, Norway, who likely died of enteric fever. Analysis of this genome against a new, significantly expanded database of related modern genomes demonstrated that Paratyphi C is descended from the ancestors of swine pathogens, serovars Choleraesuis and Typhisuis, together forming the Para C Lineage. Our results indicate that Paratyphi C has been a pathogen of humans for at least 1,000 years, and may have evolved after zoonotic transfer from swine during the Neolithic period.
| Item Type: | Dataset | |||||||||||||||
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| Subjects: | Q Science > QR Microbiology | |||||||||||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | |||||||||||||||
| Type of Data: | Table about site in RKS4594, branch, #events leading to paratyphi c, typhisuis & choleraesuis, etc | |||||||||||||||
| Library of Congress Subject Headings (LCSH): | Typhoid fever -- Genetic aspects -- History, Typhoid fever -- Trondheim (Norway) -- 13th century | |||||||||||||||
| Publisher: | University of Warwick, Warwick Medical School | |||||||||||||||
| Official Date: | 4 May 2018 | |||||||||||||||
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| Status: | Not Peer Reviewed | |||||||||||||||
| Publication Status: | Published | |||||||||||||||
| Media of Output (format): | .xlsx | |||||||||||||||
| Access rights to Published version: | Open Access (Creative Commons) | |||||||||||||||
| Copyright Holders: | University of Warwick | |||||||||||||||
| Description: | SNPs in the core genome of the Para C Lineage plus Birkenhead. |
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| Date of first compliant deposit: | 2 May 2018 | |||||||||||||||
| Date of first compliant Open Access: | 2 May 2018 | |||||||||||||||
| RIOXX Funder/Project Grant: |
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