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Policy lessons from quantitative modeling of leprosy
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Medley, Graham, Blok, David J., Crump, Ronald, Hollingsworth, T. Déirdre, Galvani, Alison P., Ndeffo-Mbah, Martial L., Porco, Travis C. and Richardus, Jan Hendrik (2018) Policy lessons from quantitative modeling of leprosy. Clinical Infectious Diseases, 66 (Supplement 4). S281-S285. doi:10.1093/cid/ciy005
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WRAP-policy-lessons-quantitative-modeling-leprosy-Medley-2018.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (1066Kb) | Preview |
Official URL: http://dx.doi.org/10.1093/cid/ciy005
Abstract
Recent mathematical and statistical modeling of leprosy incidence data provides estimates of the current undiagnosed population and projections of diagnosed cases, as well as ongoing transmission. Furthermore, modeling studies have been used to evaluate the effectiveness of proposed intervention strategies, such as postleprosy exposure prophylaxis and novel diagnostics, relative to current approaches. Such modeling studies have revealed both a slow decline of new cases and a substantial pool of undiagnosed infections. These findings highlight the need for active case detection, particularly targeting leprosy foci, as well as for continued research into innovative accurate, rapid, and cost-effective diagnostics. As leprosy incidence continues to decline, targeted active case detection primarily in foci and connected areas will likely become increasingly important.
| Item Type: | Journal Article | |||||||||
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| Subjects: | R Medicine > RC Internal medicine | |||||||||
| Divisions: | Faculty of Science > Life Sciences (2010- ) | |||||||||
| Library of Congress Subject Headings (LCSH): | Leprosy -- Diagnosis -- Mathematical models, Leprosy -- Transmission -- Mathematical models | |||||||||
| Journal or Publication Title: | Clinical Infectious Diseases | |||||||||
| Publisher: | Oxford University Press | |||||||||
| ISSN: | 1537-6591 | |||||||||
| Official Date: | 1 June 2018 | |||||||||
| Dates: |
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| Date of first compliant deposit: | 11 June 2018 | |||||||||
| Volume: | 66 | |||||||||
| Number: | Supplement 4 | |||||||||
| Page Range: | S281-S285 | |||||||||
| DOI: | 10.1093/cid/ciy005 | |||||||||
| Status: | Peer Reviewed | |||||||||
| Publication Status: | Published | |||||||||
| Access rights to Published version: | Open Access | |||||||||
| RIOXX Funder/Project Grant: |
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