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Is there an association between early weight status and utility based health-related quality of life in young children?
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Tan, Eng J., Brown, Victoria, Petrou, Stavros, D'Souza, Mario, Moodie, Marj L., Wen, Li M., Baur, Louise A., Rissel, Chris and Hayes, Alison J. (2018) Is there an association between early weight status and utility based health-related quality of life in young children? Quality of Life Research, 27 (11). pp. 2851-2858. doi:10.1007/s11136-018-1932-2
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WRAP-association-early-weight-status-utility-health-quality-children-Petrou-2018.pdf - Accepted Version - Requires a PDF viewer. Download (644Kb) | Preview |
Official URL: https://doi.org/10.1007/s11136-018-1932-2
Abstract
Purpose
Few studies focus on the health-related quality of life (HRQoL) of preschool children with overweight or obesity. This is relevant for evaluation of obesity prevention trials using a quality-adjusted life year (QALY) framework. This study examined the association between weight status in the preschool years and HRQoL at age 5 years, using a preference-based instrument.
Methods
HRQoL [based on parent proxy version of the Health Utilities Index Mark 3 (HUI3)] and weight status were measured in children born in Australia between 2007 and 2009. Children’s health status was scored across eight attributes of the HUI3—vision, hearing, speech, ambulation, dexterity, emotion, cognition and pain, and these were used to calculate a multi-attribute utility score. Ordinary least squares (OLS), Tobit and two-part regressions were used to model the association between weight status and multi-attribute utility.
Results
Of the 368 children for whom weight status and HUI3 data were available, around 40% had overweight/obesity. After adjusting for child’s sex, maternal education, marital status and household income, no significant association between weight status in the preschool years and multi-attribute utility scores at 5 years was found.
Conclusions
Alternative approaches for capturing the effects of weight status in the preschool years on preference-based HRQoL outcomes should be tested. The application of the QALY framework to economic evaluations of obesity-related interventions in young children should also consider longitudinal effects over the life-course.
| Item Type: | Journal Article | ||||||||||||
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| Subjects: | R Medicine > RJ Pediatrics | ||||||||||||
| Divisions: | Faculty of Medicine > Warwick Medical School > Health Sciences > Clinical Trials Unit Faculty of Medicine > Warwick Medical School > Health Sciences |
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| Library of Congress Subject Headings (LCSH): | Obesity in children -- Austrália, Preschool children -- Health aspects -- Austrália, Quality of life -- Austrália | ||||||||||||
| Journal or Publication Title: | Quality of Life Research | ||||||||||||
| Publisher: | Springer Netherlands | ||||||||||||
| ISSN: | 0962-9343 | ||||||||||||
| Official Date: | November 2018 | ||||||||||||
| Dates: |
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| Date of first compliant deposit: | 19 June 2018 | ||||||||||||
| Volume: | 27 | ||||||||||||
| Number: | 11 | ||||||||||||
| Page Range: | pp. 2851-2858 | ||||||||||||
| DOI: | 10.1007/s11136-018-1932-2 | ||||||||||||
| Status: | Peer Reviewed | ||||||||||||
| Publication Status: | Published | ||||||||||||
| Access rights to Published version: | Restricted or Subscription Access | ||||||||||||
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