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Is there an association between early weight status and utility based health-related quality of life in young children?

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Tan, Eng J., Brown, Victoria, Petrou, Stavros, D'Souza, Mario, Moodie, Marj L., Wen, Li M., Baur, Louise A., Rissel, Chris and Hayes, Alison J. (2018) Is there an association between early weight status and utility based health-related quality of life in young children? Quality of Life Research, 27 (11). pp. 2851-2858. doi:10.1007/s11136-018-1932-2

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Official URL: https://doi.org/10.1007/s11136-018-1932-2

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Abstract

Purpose

Few studies focus on the health-related quality of life (HRQoL) of preschool children with overweight or obesity. This is relevant for evaluation of obesity prevention trials using a quality-adjusted life year (QALY) framework. This study examined the association between weight status in the preschool years and HRQoL at age 5 years, using a preference-based instrument.

Methods

HRQoL [based on parent proxy version of the Health Utilities Index Mark 3 (HUI3)] and weight status were measured in children born in Australia between 2007 and 2009. Children’s health status was scored across eight attributes of the HUI3—vision, hearing, speech, ambulation, dexterity, emotion, cognition and pain, and these were used to calculate a multi-attribute utility score. Ordinary least squares (OLS), Tobit and two-part regressions were used to model the association between weight status and multi-attribute utility.

Results

Of the 368 children for whom weight status and HUI3 data were available, around 40% had overweight/obesity. After adjusting for child’s sex, maternal education, marital status and household income, no significant association between weight status in the preschool years and multi-attribute utility scores at 5 years was found.

Conclusions

Alternative approaches for capturing the effects of weight status in the preschool years on preference-based HRQoL outcomes should be tested. The application of the QALY framework to economic evaluations of obesity-related interventions in young children should also consider longitudinal effects over the life-course.

Item Type: Journal Article
Subjects: R Medicine > RJ Pediatrics
Divisions: Faculty of Medicine > Warwick Medical School > Health Sciences > Clinical Trials Unit
Faculty of Medicine > Warwick Medical School > Health Sciences
Library of Congress Subject Headings (LCSH): Obesity in children -- Austrália, Preschool children -- Health aspects -- Austrália, Quality of life -- Austrália
Journal or Publication Title: Quality of Life Research
Publisher: Springer Netherlands
ISSN: 0962-9343
Official Date: November 2018
Dates:
DateEvent
November 2018Published
10 July 2018Available
18 June 2018Accepted
Volume: 27
Number: 11
Page Range: pp. 2851-2858
DOI: 10.1007/s11136-018-1932-2
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
#393112National Health and Medical Research Council (NHMRC)http://dx.doi.org/10.13039/501100000925
#1003780National Health and Medical Research Council (NHMRC)http://dx.doi.org/10.13039/501100000925
#1101675National Health and Medical Research Council (NHMRC)http://dx.doi.org/10.13039/501100000925
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