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Socio-economic deprivation and survival in bladder cancer
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Begum, G., Dunn, J. A., Bryan, R. T., Bathers, S. and Wallace, D. M. A. (2004) Socio-economic deprivation and survival in bladder cancer. BJU International, 94 (4). pp. 539-543. doi:10.1111/j.1464-410X.2004.04997.x ISSN 1464-1603.
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Official URL: https://doi.org/10.1111/j.1464-410X.2004.04997.x
Abstract
OBJECTIVES: To investigate the relationship between deprivation, delay and survival from bladder cancer in the West Midlands, as socio-economic deprivation is associated with worse survival in many malignancies, and it has been suggested that treatment differences and delay in seeking care are major contributing causes. PATIENTS AND METHODS: Data were prospectively collected on 1537 newly diagnosed cases of urothelial cancer presenting in the West Midlands between January 1991 and June 1992. Survival was censored at 31 July 2000, when 785 (51%) patients had died. The influence of deprivation on survival was explored using cause-specific and all-cause mortality. RESULTS: Patients in less affluent groups had significantly worse survival than patients in more affluent groups when considering deaths from all causes (P = 0.02), which held true when adjusting for independent prognostic factors (age, smoking history, and tumour grade, stage, type and size). Bladder cancer-specific mortality showed no significant difference between socio-economic groups (P = 0.30). CONCLUSION: Socio-economic deprivation is a significant predictor of survival when death from all causes is considered. However, this does not hold true for bladder cancer-specific death. The perceived differences in treatment and delay between socio-economic groups do not seem to occur for bladder cancer in the West Midlands.
| Item Type: | Journal Article | ||||||
|---|---|---|---|---|---|---|---|
| Subjects: | R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) | ||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit | ||||||
| Journal or Publication Title: | BJU International | ||||||
| Publisher: | Wiley-Blackwell Publishing Ltd. | ||||||
| ISSN: | 1464-1603 | ||||||
| Official Date: | 25 August 2004 | ||||||
| Dates: |
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| Volume: | 94 | ||||||
| Number: | 4 | ||||||
| Page Range: | pp. 539-543 | ||||||
| DOI: | 10.1111/j.1464-410X.2004.04997.x | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Access rights to Published version: | Restricted or Subscription Access |
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