Skip to content Skip to navigation
University of Warwick
  • Study
  • |
  • Research
  • |
  • Business
  • |
  • Alumni
  • |
  • News
  • |
  • About

University of Warwick
Publications service & WRAP

Highlight your research

  • WRAP
    • Home
    • Search WRAP
    • Browse by Warwick Author
    • Browse WRAP by Year
    • Browse WRAP by Subject
    • Browse WRAP by Department
    • Browse WRAP by Funder
    • Browse Theses by Department
  • Publications Service
    • Home
    • Search Publications Service
    • Browse by Warwick Author
    • Browse Publications service by Year
    • Browse Publications service by Subject
    • Browse Publications service by Department
    • Browse Publications service by Funder
  • Help & Advice
University of Warwick

The Library

  • Login
  • Admin

Cigarette smoking and histological outcome in wom with mildly dyskaryotic cervical smears

Tools
- Tools
+ Tools

Luesley, D., Blomfield, P., Dunn, Janet A., Shafi, M., Chenoy, R. and Buxton, J. (1994) Cigarette smoking and histological outcome in wom with mildly dyskaryotic cervical smears. BJOG: An International Journal of Obstetrics & Gynaecology, 101 (1). pp. 49-52. doi:10.1111/j.1471-0528.1994.tb13009.x

Research output not available from this repository, contact author.
Official URL: https://doi.org/10.1111/j.1471-0528.1994.tb13009.x

Request Changes to record.

Abstract

Objective To determine which patient related variables, available at the point of referral, predict the presence of high grade intraepithelial neoplasia when the smear result is mild dyskaryosis with or without co‐existent koilocytosis.

Design Multivariate analysis of prospective programme trial.

Setting Academic Department Colposcopy clinics at Dudley Road Hospital, Birmingham, UK.

Subjects One hundred and sixty‐seven women, whose worst ever cervical smear was mild dyskaryosis with or without koilocytosis, referred to colposcopy clinics. All the women had complete data sets, as determined by the format of an ongoing programme, and all were treated by diathermy loop excision of the cervical transformation zone.

Main outcome measures Age, parity, contraceptive practice, smoking habit, duration of abnormal cytology and the grade of histology in the excised transformation zone.

Results Forty‐seven out of 78 (60%) smokers, compared with 18 out of 73 (25%) nonsmokers, had high grade disease. The other variables considered in the analysis were not significant or very weakly associated with histological grade when analysed in a univariate analysis. Stepwise logistic regression identified cigarette smoking as a powerful independent predictor of high grade disease.

Conclusion These data suggest a strong association between smoking and high grade intraepithelial neoplasia in a population of women whose worst ever smear report was mild dyskaryosis. Smoking is a variable that could be built into models to facilitate referral for colposcopic assessment.

Item Type: Journal Article
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine > Warwick Medical School > Health Sciences > Clinical Trials Unit
Faculty of Medicine > Warwick Medical School > Health Sciences
Faculty of Medicine > Warwick Medical School
Journal or Publication Title: BJOG: An International Journal of Obstetrics & Gynaecology
Publisher: Wiley-Blackwell Publishing, Inc
ISSN: 1470-0328
Official Date: 1 January 1994
Dates:
DateEvent
1 January 1994Published
6 September 1993Accepted
Volume: 101
Number: 1
Page Range: pp. 49-52
DOI: 10.1111/j.1471-0528.1994.tb13009.x
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access

Request changes or add full text files to a record

Repository staff actions (login required)

View Item View Item
twitter

Email us: wrap@warwick.ac.uk
Contact Details
About Us