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Management of advanced nodal disease in patients treated with primary chemoradiotherapy
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Mehanna, H., Wong, W. L. and Dunn, Janet A. (2016) Management of advanced nodal disease in patients treated with primary chemoradiotherapy. Current Opinion in Oncology, 28 (3). pp. 201-204. doi:10.1097/CCO.0000000000000283
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Official URL: https://doi.org/10.1097/CCO.0000000000000283
Abstract
Purpose of review The management of advanced nodal disease in patients treated with chemoradiotherapy has been a controversial topic for many years. New data have recently been reported, including the results of a multicentre randomized trial making this review timely. Recent findings The PET-NECK trial showed that PET-computer tomography (CT) surveillance is as effective as planned neck dissection in terms of overall survival, but results in much fewer neck dissections, less complications and is more cost effective. Cost-effectiveness data from a single centre study demonstrated that strategies that include PET-CT were more effective than CT-alone-guided strategies. Summary There is now level 1 evidence to support image-guided surveillance strategies as the standard of care for advanced nodal disease in patients treated with primary chemoradiotherapy. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.
| Item Type: | Journal Item | ||||
|---|---|---|---|---|---|
| Subjects: | R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) | ||||
| Divisions: | Faculty of Medicine > Warwick Medical School > Health Sciences > Clinical Trials Unit Faculty of Medicine > Warwick Medical School > Health Sciences Faculty of Medicine > Warwick Medical School |
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| Journal or Publication Title: | Current Opinion in Oncology | ||||
| Publisher: | Lippincott Williams and Wilkins | ||||
| ISSN: | 10408746 | ||||
| Official Date: | 2016 | ||||
| Dates: |
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| Volume: | 28 | ||||
| Number: | 3 | ||||
| Page Range: | pp. 201-204 | ||||
| DOI: | 10.1097/CCO.0000000000000283 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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