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Management of advanced nodal disease in patients treated with primary chemoradiotherapy

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Mehanna, H., Wong, W. L. and Dunn, Janet A. (2016) Management of advanced nodal disease in patients treated with primary chemoradiotherapy. Current Opinion in Oncology, 28 (3). pp. 201-204. doi:10.1097/CCO.0000000000000283

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Official URL: https://doi.org/10.1097/CCO.0000000000000283

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Abstract

Purpose of review The management of advanced nodal disease in patients treated with chemoradiotherapy has been a controversial topic for many years. New data have recently been reported, including the results of a multicentre randomized trial making this review timely. Recent findings The PET-NECK trial showed that PET-computer tomography (CT) surveillance is as effective as planned neck dissection in terms of overall survival, but results in much fewer neck dissections, less complications and is more cost effective. Cost-effectiveness data from a single centre study demonstrated that strategies that include PET-CT were more effective than CT-alone-guided strategies. Summary There is now level 1 evidence to support image-guided surveillance strategies as the standard of care for advanced nodal disease in patients treated with primary chemoradiotherapy. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.

Item Type: Journal Item
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions: Faculty of Medicine > Warwick Medical School > Health Sciences > Clinical Trials Unit
Faculty of Medicine > Warwick Medical School > Health Sciences
Faculty of Medicine > Warwick Medical School
Journal or Publication Title: Current Opinion in Oncology
Publisher: Lippincott Williams and Wilkins
ISSN: 10408746
Official Date: 2016
Dates:
DateEvent
2016Published
Volume: 28
Number: 3
Page Range: pp. 201-204
DOI: 10.1097/CCO.0000000000000283
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access

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