The Library
Characterization of high- and low-grade cervical intraepithelial neoplasia
Tools
Tools
Tools
Shafi, M. I., Dunn, Janet A., Finn, C. B., Kehoe, S., Buxton, E. J., Jordan, J. A. and Luesley, D. M. (1993) Characterization of high- and low-grade cervical intraepithelial neoplasia. International Journal of Gynecological Cancer, 3 (4). pp. 203-207. doi:10.1046/j.1525-1438.1993.03040203.x
Research output not available from this repository, contact author.
Official URL: https://doi.org/10.1046/j.1525-1438.1993.03040203....
Abstract
A need exists to characterize the various grades of cervical intrapithelial neoplasia (CIN), and attempt to differentiate between high‐ and low‐grade lesions, that may have different behavioral and progressive potentials. The identification of patients with high‐ or low‐grade CIN is useful, as it may allow identification of those patients that have true cancer precursors. Fifty patients referred for colposcopy with abnormal cytology were studied. Univariate analysis identified three factors as important predictors of histologic grade; the colposcopic opinion, lesion surface area and the index cytology (P < 0.005). Colposcopic opinion was associated with the index cytology (P < 0.01) and the lesion surface area (P < 0.005). Only the colposcopic opinion and the index cytologic smear appeared in the final model using a stepwise logistic regression analysis, indicating their independent prognostic importance in prediction of grade of abnormality in cervical intraepithelial neoplasia. The study demonstrates the value of colposcopic training and experience being necessary prior to utilizing excisional treatment methods if overtreatment is to be avoided.
| Item Type: | Journal Article | ||||||
|---|---|---|---|---|---|---|---|
| Subjects: | R Medicine > RG Gynecology and obstetrics | ||||||
| Divisions: | Faculty of Medicine > Warwick Medical School > Health Sciences > Clinical Trials Unit Faculty of Medicine > Warwick Medical School > Health Sciences Faculty of Medicine > Warwick Medical School |
||||||
| Journal or Publication Title: | International Journal of Gynecological Cancer | ||||||
| Publisher: | Lippincott Williams & Wilkins | ||||||
| ISSN: | 1048-891X | ||||||
| Official Date: | August 1993 | ||||||
| Dates: |
|
||||||
| Volume: | 3 | ||||||
| Number: | 4 | ||||||
| Page Range: | pp. 203-207 | ||||||
| DOI: | 10.1046/j.1525-1438.1993.03040203.x | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Access rights to Published version: | Restricted or Subscription Access |
Request changes or add full text files to a record
Repository staff actions (login required)
 |
View Item |
