Health utilities in evaluating intervention in the sleep apnoea/hypopnoea syndrome
UNSPECIFIED. (2002) Health utilities in evaluating intervention in the sleep apnoea/hypopnoea syndrome. EUROPEAN RESPIRATORY JOURNAL, 20 (5). pp. 1233-1238. ISSN 0903-1936Full text not available from this repository.
Official URL: http://dx.doi.org/10.1183/09031936.00.00014401
Formulating a rational health policy necessitates the ability to compare between different healthcare interventions and disease scenarios. Continuous positive airway pressure (CPAP) therapy with a conservative lifestyle strategy in sleep apnoea/hypopnoea syndrome (SAHS) was evaluated using health utility and quality-adjusted life years (QALYs) as outcome measures.
A total 71 SAHS (apnoea/hypopnoea index greater than or equal to15 h(-1)) patients completed a randomised, parallel group study over 3 months using utilities derived by the standard gamble approach (U-sg) and European quality of life questionnaire (Euroqol) (U-eq).
The severely impaired health status at baseline improved by 23% (U-sg 0.32 to 0.55) adding 8 QALYs in the CPAP group, compared to a 4% improvement with 4.7 QALYs added in the lifestyle group (U-sg 0.31 to 0.35). The U-eq showed a marginal change with CPAP (0.73 to 0.77) but did not demonstrate any improvement with lifestyle intervention.
The health status impairment in sleep apnoea/hypopnoea syndrome patients is markedly improved by continuous positive airway pressure compared to a modest improvement with conservative lifestyle strategies using the standard gamble utility, which may he incorporated in effectiveness and economic analyses. The European quality of life questionnaire did not reflect a similar degree of impact and is probably not useful in this population.
|Item Type:||Journal Article|
|Subjects:||R Medicine > RC Internal medicine|
|Journal or Publication Title:||EUROPEAN RESPIRATORY JOURNAL|
|Publisher:||EUROPEAN RESPIRATORY SOC JOURNALS LTD|
|Official Date:||November 2002|
|Number of Pages:||6|
|Page Range:||pp. 1233-1238|
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