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Health utilities in evaluating intervention in the sleep apnoea/hypopnoea syndrome
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UNSPECIFIED. (2002) Health utilities in evaluating intervention in the sleep apnoea/hypopnoea syndrome. EUROPEAN RESPIRATORY JOURNAL, 20 (5). pp. 1233-1238. ISSN 0903-1936
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Official URL: http://dx.doi.org/10.1183/09031936.00.00014401
Abstract
Formulating a rational health policy necessitates the ability to compare between different healthcare interventions and disease scenarios. Continuous positive airway pressure (CPAP) therapy with a conservative lifestyle strategy in sleep apnoea/hypopnoea syndrome (SAHS) was evaluated using health utility and quality-adjusted life years (QALYs) as outcome measures. A total 71 SAHS (apnoea/hypopnoea index greater than or equal to15 h(-1)) patients completed a randomised, parallel group study over 3 months using utilities derived by the standard gamble approach (U-sg) and European quality of life questionnaire (Euroqol) (U-eq). The severely impaired health status at baseline improved by 23% (U-sg 0.32 to 0.55) adding 8 QALYs in the CPAP group, compared to a 4% improvement with 4.7 QALYs added in the lifestyle group (U-sg 0.31 to 0.35). The U-eq showed a marginal change with CPAP (0.73 to 0.77) but did not demonstrate any improvement with lifestyle intervention. The health status impairment in sleep apnoea/hypopnoea syndrome patients is markedly improved by continuous positive airway pressure compared to a modest improvement with conservative lifestyle strategies using the standard gamble utility, which may he incorporated in effectiveness and economic analyses. The European quality of life questionnaire did not reflect a similar degree of impact and is probably not useful in this population.
| Item Type: | Journal Article |
|---|---|
| Subjects: | R Medicine > RC Internal medicine |
| Journal or Publication Title: | EUROPEAN RESPIRATORY JOURNAL |
| Publisher: | EUROPEAN RESPIRATORY SOC JOURNALS LTD |
| ISSN: | 0903-1936 |
| Date: | November 2002 |
| Volume: | 20 |
| Number: | 5 |
| Number of Pages: | 6 |
| Page Range: | pp. 1233-1238 |
| Identification Number: | 10.1183/09031936.00.00014401 |
| Publication Status: | Published |
| URI: | http://wrap.warwick.ac.uk/id/eprint/10422 |
Data sourced from Thomson Reuters' Web of Knowledge
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