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Development of an outcome prediction tool for patients considering a total knee replacement - the Knee Outcome Prediction Study (KOPS)
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Barlow, T., Dunbar, M., Sprowson, A., Parsons, Nicholas R. and Griffin, Damian R. (2014) Development of an outcome prediction tool for patients considering a total knee replacement - the Knee Outcome Prediction Study (KOPS). BMC musculoskeletal disorders, 15 (451). doi:10.1186/1471-2474-15-451 ISSN 1471-2474.
An open access version can be found in:
Official URL: https://doi.org/10.1186/1471-2474-15-451
Abstract
Background: Knee osteoarthritis affects 10% of the UK population over 55 years, resulting in pain and decreased quality of life. Knee replacement surgery has a proven benefit, with over 85,000 performed each year in the UK; however, approximately 17% of people are dissatisfied after surgery. Consequently, some Primary Care Trusts have reduced the funding available for knee replacements. Most previous work has focused on the effect of different prostheses and treatment protocols on patient's outcome. However, this has been unable to account for all the variability and there is growing evidence that patient factors may significantly affect outcome. How to identify these at risk patients has been identified as a research priority by the National Institute of Clinical Excellence, the British Orthopedic Association, and the National Joint Registry. The aim of this study is to develop a clinically appropriate outcome prediction tool based on measurable predictors affecting outcome.
Methods/design: We propose a prospective cohort study, designed to develop and validate an outcome prediction tool based on patient factors. Six hundred patients who are scheduled for total knee replacement secondary to primary osteoarthritis will be recruited before surgery from all six hospitals (NHS and private) that provide total knee replacements to the population of Coventry and Warwickshire (UK). Patients will complete a baseline assessment of patient factors before their operation and will be followed up at 6 and 12 months post surgery.
Discussion: A clinically appropriate outcome prediction tool will allow patients to make a more informed decision regarding surgery. Aligning patient expectations with a realistic prediction of outcome should improve satisfaction. Ultimately, this project is likely to inform national policy making and regional service provision.
| Item Type: | Journal Article | ||||||
|---|---|---|---|---|---|---|---|
| Subjects: | R Medicine > RD Surgery | ||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Journal or Publication Title: | BMC musculoskeletal disorders | ||||||
| Publisher: | Biomed Central | ||||||
| ISSN: | 1471-2474 | ||||||
| Official Date: | 23 December 2014 | ||||||
| Dates: |
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| Volume: | 15 | ||||||
| Number: | 451 | ||||||
| DOI: | 10.1186/1471-2474-15-451 | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Access rights to Published version: | Restricted or Subscription Access | ||||||
| Date of first compliant deposit: | 17 July 2018 | ||||||
| Funder: | Arthritis Research UK | ||||||
| Grant number: | 20569 | ||||||
| Open Access Version: |
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