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Does malalignment affect revision rate in total knee replacements : a systematic review of the literature

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Hadi, M., Barlow, T., Ahmed, I., Dunbar, M., McCulloch, P. and Griffin, Damian R. (2015) Does malalignment affect revision rate in total knee replacements : a systematic review of the literature. Springerplus, 4 (835). pp. 1-12. doi:10.1186/s40064-015-1604-4 ISSN 2193-1801.

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Official URL: https://doi.org/10.1186/s40064-015-1604-4

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Abstract

To ensure implant durability following Modern total knee replacement (TKR) surgery, one long held principle in condylar total knee arthroplasty is positioning the components in alignment with the mechanical axis and restoring the overall limb alignment to 180 degrees +/- 3 degrees. However, this view has been challenged recently. Given the high number of TKR performed, clarity on this integral aspect of the procedure is necessary. To investigate the association between malalignment following primary TKR and revision rates. A systematic review of the literature was conducted using a computerised literature search of Medline, CINHAL, and EMBASE to identify English-language studies published from 2000 through to 2014. Studies with adequate information on the correlation between malalignment and revision rate with a minimum follow-up of 6 months were considered for inclusion. A study protocol, including the detailed search strategy was published on the PROSPERO database for systematic reviews. From an initial 2107 citations, eight studies, with variable methodological qualities, were eligible for inclusion. Collectively, nine parameters of alignment were studied, and 20 assessments were made between an alignment parameter and revision rate. Four out of eight studies demonstrated an association between a malalignment parameter and increased revision rates. In the coronal plane, only three studies assessed the mechanical axis. None of these studies found an association with revision rates, whereas four of the five studies investigating the anatomical axis found an association between malalignment and increased revision rate. This study demonstrates the effect of malalignment on revision rates is likely to be modest. Interestingly, studies that used mechanical alignment in the coronal plane demonstrated no association with revision rates. This questions the premise of patient specific instrumentation devices based on the mechanically aligned knee when considering revision as the endpoint.

Item Type: Journal Article
Subjects: R Medicine > R Medicine (General)
R Medicine > RD Surgery
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Journal or Publication Title: Springerplus
Publisher: Springer International Publishing
ISSN: 2193-1801
Official Date: 30 December 2015
Dates:
DateEvent
30 December 2015Published
11 December 2015Accepted
Volume: 4
Number: 835
Page Range: pp. 1-12
DOI: 10.1186/s40064-015-1604-4
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Date of first compliant deposit: 17 July 2018
Open Access Version:
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