UNSPECIFIED. (2002) Modeling dynamic and network heterogeneities in the spread of sexually transmitted diseases. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 99 (20). pp. 13330-13335. ISSN 0027-8424

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Abstract

A wide range of communicable human diseases can be considered as spreading through a network of possible transmission routes. The implied network structure is vital in determining disease dynamics, especially when the average number of connections per individual is small as is the case for many sexually transmitted diseases (STDs). Here we develop an intuitive mathematical framework to deal with the heterogeneities implicit within contact networks and those that arise because of the infection process. These models are compared with full stochastic simulations and show excellent agreement across a wide range of parameters. We show how such models can be used to estimate parameters of epidemiological importance, and how they can be extended to examine the effectiveness of various control strategies, in particular screening programs and contact tracing.

Item Type:	Journal Article
Subjects:	Q Science
Journal or Publication Title:	PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publisher:	NATL ACAD SCIENCES
ISSN:	0027-8424
Date:	1 October 2002
Volume:	99
Number:	20
Number of Pages:	6
Page Range:	pp. 13330-13335
Identification Number:	10.1073/pnas.202244299
Publication Status:	Published
URI:	http://wrap.warwick.ac.uk/id/eprint/10508

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