The use of microarray technology for the analysis of Streptococcus pneumoniae
UNSPECIFIED (2002) The use of microarray technology for the analysis of Streptococcus pneumoniae. In: 1st Symposium of the Wellcome Trust Funded Mult-Collaborative Microbial Pathogen Microrray Facility, CAMBRIDGE, ENGLAND, MAY 23-24, 2002. Published in: COMPARATIVE AND FUNCTIONAL GENOMICS, 3 (4). pp. 366-368.Full text not available from this repository.
Official URL: http://dx.doi.org/10.1002/cfg.190
Streptococcus pneumoniae is an important human pathogen associated with pneumonia, septicaemia, meningitis and otitis media. It is estimated to result in over 3 million child deaths worldwide every year and an even greater number of deaths among the elderly. Prior to the complete sequencing of the genomes of S. pneumoniae TIGR4 (serotype 4) and S. pneumoniae R6 (serotype 2), we designed a custom miniarray consisting of 497 pneumococcal genes. The overall objectives of our microarray investigations were, first, to assess the genetic diversity between different S. pneumoniae serotypes, clinical isolates and also different Streptococcus species; second, we aimed to use microarray technology to examine the mechanisms by which environmental factors influence pneumococcal gene expression, and ultimately to further the understanding of how these changes in gene expression are achieved and how they may after the virulence of the organism. Copyright (C) John Wiley Sons, Ltd.
|Item Type:||Conference Item (UNSPECIFIED)|
|Subjects:||Q Science > QD Chemistry
T Technology > TP Chemical technology
Q Science > QH Natural history > QH426 Genetics
|Journal or Publication Title:||COMPARATIVE AND FUNCTIONAL GENOMICS|
|Publisher:||JOHN WILEY & SONS LTD|
|Number of Pages:||3|
|Page Range:||pp. 366-368|
|Title of Event:||1st Symposium of the Wellcome Trust Funded Mult-Collaborative Microbial Pathogen Microrray Facility|
|Location of Event:||CAMBRIDGE, ENGLAND|
|Date(s) of Event:||MAY 23-24, 2002|
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