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Survival and the use and costs of hospital services for London AIDS patients treated with AZT
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Beck, E. J., Kupek, E. J., Petrou, Stavros, Wadsworth, J., Miller, D. L., Pinching, A. J. and Harris, J. R. W. (1996) Survival and the use and costs of hospital services for London AIDS patients treated with AZT. International Journal of STD and AIDS, 7 (7). pp. 507-512. doi:10.1258/0956462961918428 ISSN 0956-4624.
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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/9116068
Abstract
The aim of this study was to evaluate the survival patterns and use and cost of hospital services of AIDS patients treated with azidothymidine (AZT) at St Mary's Hospital, London. A retrospective analysis of inpatient and outpatient case notes was performed, as was a survey of HIV-related care costs in 37 clinical departments. Of the 183 AIDS patients managed between 1 January 1987 and 30 September 1989, 132 were treated with AZT and 51 without AZT. Mean age at time of AIDS diagnosis for these predominantly homosexual men was 37.5 years for those treated with AZT compared with 40.7 years for those not on AZT. Median survival time from date of AIDS diagnosis was significantly longer for patients treated with AZT compared with those not treated with AZT (23 vs 13.5 months, P = 0.0004). The interval from diagnosis of HIV infection to date of AIDs diagnosis did not differ significantly between groups. Inpatient and outpatient use of services was greater for those receiving AZT than for those who did not. Costs reflected this increased use of services and the costs for those treated with AZT were £3061 per AIDS patient-year higher compared with AIDS patients not receiving AZT; 36% of this cost was directly attributable to the cost of AZT itself. The introduction of AZT into routine clinical practice seems to have been a cost-effective intervention though it has been associated with an increased use of hospital services and associated costs per AIDS patient-year as well as increased survival time from AIDS diagnosis.
| Item Type: | Journal Article | ||||||
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| Subjects: | R Medicine > R Medicine (General) | ||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Journal or Publication Title: | International Journal of STD and AIDS | ||||||
| ISSN: | 0956-4624 | ||||||
| Official Date: | December 1996 | ||||||
| Dates: |
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| Volume: | 7 | ||||||
| Number: | 7 | ||||||
| Page Range: | pp. 507-512 | ||||||
| DOI: | 10.1258/0956462961918428 | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Access rights to Published version: | Restricted or Subscription Access |
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