Adetokunboh, Olatunji O., Uthman, Olalekan A. and Wiysonge, Charles S. (2018) Non-uptake of childhood vaccination among the children of HIV-infected mothers in sub-Saharan Africa : a multilevel analysis. Human Vaccines & Immunotherapeutics, 14 (10). pp. 2405-2413. doi:10.1080/21645515.2018.1502524 ISSN 2164-5515.

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Abstract

The aim of this study was to develop and test models for non–uptake of three doses of diphtheria-tetanus-pertussis containing vaccines (DTP3) among children of women living with HIV in sub-Saharan Africa. The study used demographic and health survey data from 27 sub-Saharan African countries that have the required HIV and immunization data sets. Multivariable logistic regression models were used to assess the relationship between individual and contextual factors associated with non-uptake of DTP3 among the children. At the individual level, the odds of non-uptake of DTP3 decreased with formal education, increasing age and access to media. The full model shows that the odds of non-uptake of DTP3 is increased among unemployed women, those living in communities with high illiteracy rate and in countries with low adult literacy level. For a child who moved to another country or community with a higher probability of DTP3 non-uptake, the median increase for the odds of DTP3 non-uptake would be 2.24% and 1.22% respectively for country and community. This study shows that individual and contextual factors contributed significantly to non-uptake of DTP3 among the children of women living with HIV. Interventions should be focused on women living with HIV who are young mothers, unemployed women, those without formal education, individuals living in communities with high illiteracy rate and in countries with low adult literacy rate. The use of mass media tools and creation of more employment opportunities for HIV-infected women could improve vaccination coverage among their children.

Item Type:	Journal Article
Subjects:	R Medicine > RJ Pediatrics
Divisions:	Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Population, Evidence & Technologies (PET) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH):	Immunization of children -- Africa, HIV-positive women -- Africa
Journal or Publication Title:	Human Vaccines & Immunotherapeutics
Publisher:	Landes Bioscience
ISSN:	2164-5515
Official Date:	23 July 2018
Dates:	Date Event 23 July 2018 Published 5 July 2018 Accepted
Volume:	14
Number:	10
Page Range:	pp. 2405-2413
DOI:	10.1080/21645515.2018.1502524
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Date of first compliant deposit:	26 July 2018
Date of first compliant Open Access:	23 July 2019
RIOXX Funder/Project Grant:	Project/Grant ID RIOXX Funder Name Funder ID UNSPECIFIED National Research Foundation http://dx.doi.org/10.13039/100011512 UNSPECIFIED South African Medical Research Council http://dx.doi.org/10.13039/501100001322 UNSPECIFIED [NIHR] National Institute for Health Research http://dx.doi.org/10.13039/501100000272

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