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One-year resource utilisation, costs and quality of life in patients with acute respiratory distress syndrome (ARDS) : secondary analysis of a randomised controlled trial
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Marti, Joachim, Hall, Peter, Hamilton, Patrick, Lamb, S. E. (Sallie E.), McCabe, Chris, Lall, Ranjit, Darbyshire, Julie, Young, Duncan and Hulme, Claire (2016) One-year resource utilisation, costs and quality of life in patients with acute respiratory distress syndrome (ARDS) : secondary analysis of a randomised controlled trial. Journal of Intensive Care, 4 (1). 56. doi:10.1186/s40560-016-0178-8 ISSN 2052-0492.
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Official URL: http://dx.doi.org/10.1186/s40560-016-0178-8
Abstract
Background
The long-term economic and quality-of-life outcomes of patients admitted to intensive care unit (ICU) with acute respiratory distress syndrome are not well understood. In this study, we investigate 1-year costs, survival and quality of life following ICU admission in patients who required mechanical ventilation for acute respiratory distress syndrome.
Methods
Economic analysis of data collected alongside a UK-based multi-centre randomised, controlled trial, aimed at comparing high-frequency oscillatory ventilation with conventional mechanical ventilation. The study included 795 critically ill patients admitted to ICU. Hospital costs were assessed using daily data. Post-hospital healthcare costs, patient out-of-pocket expenses, lost earnings of survivors and their carers and health-related quality of life were assessed using follow-up surveys.
Results
The mean cost of initial ICU stay was £26,857 (95 % CI £25,222-£28,491), and the average daily cost in ICU was £1738 (CI £1667-£1810). Following hospital discharge, the average 1-year cost among survivors was £7523 (CI £5692-£9354). The mean societal cost at 1 year was £44,077 (£41,168-£46,985), and the total societal cost divided by the number of 1-year survivors was £90,206. Survivors reported significantly lower health-related quality of life than the age- and sex-matched reference population, and this difference was more marked in younger patients.
Conclusions
Given the high costs and low health-related quality of life identified, there is significant scope for further research aimed at improving care in this in-need patient group.
| Item Type: | Journal Article | |||||||||
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| Subjects: | R Medicine > RC Internal medicine | |||||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Respiratory distress syndrome -- Treatment -- Economic aspects, Respiratory distress syndrome -- Patients, Quality of life | |||||||||
| Journal or Publication Title: | Journal of Intensive Care | |||||||||
| Publisher: | BioMed Central | |||||||||
| ISSN: | 2052-0492 | |||||||||
| Official Date: | 11 August 2016 | |||||||||
| Dates: |
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| Volume: | 4 | |||||||||
| Number: | 1 | |||||||||
| Article Number: | 56 | |||||||||
| DOI: | 10.1186/s40560-016-0178-8 | |||||||||
| Status: | Not Peer Reviewed | |||||||||
| Publication Status: | Published | |||||||||
| Access rights to Published version: | Open Access (Creative Commons) | |||||||||
| Date of first compliant deposit: | 27 July 2018 | |||||||||
| Date of first compliant Open Access: | 1 August 2018 | |||||||||
| RIOXX Funder/Project Grant: |
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