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Development of a common outcome data set for fall injury prevention trials : the prevention of falls network Europe consensus

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Lamb, S. E. (Sallie E.), Jorsten, Ellen C., Hauer, Klaus and Becker, Clemens (2005) Development of a common outcome data set for fall injury prevention trials : the prevention of falls network Europe consensus. Journal of the American Geriatrics Society, 53 (9). pp. 1618-1622. doi:10.1111/j.1532-5415.2005.53455.x

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Official URL: http://dx.doi.org/10.1111/j.1532-5415.2005.53455.x

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Abstract

The prevention of injury associated with falls in older people is a public health target in many countries around the world. Although there is good evidence that interventions such as multifactorial fall prevention and individually prescribed exercise are effective in reducing falls, the effect on serious injury rates is unclear. Historically, trials have not been adequately powered to detect injury endpoints, and variations in case definition across trials have hindered meta-analysis. It is possible that fall-prevention strategies have limited effect on falls that result in injuries or are ineffective in populations who are at a higher risk of injury. Further research is required to determine whether fall-prevention interventions can reduce serious injuries. Prevention of Falls Network Europe (ProFaNE) is a collaborative project to reduce the burden of fall injury in older people through excellence in research and promotion of best practice (www.profane.eu.org). The European Commission funds the network, which links clinicians, members of the public, and researchers worldwide. The aims are to identify major gaps in knowledge in fall injury prevention and to facilitate the collaboration necessary for large-scale clinical research activity, including clinical trials, comparative research, and prospective meta-analysis. Work is being undertaken in a 4-year program. As a first step, the development of a common set of outcome definitions and measures for future trials or meta-analysis was considered. © 2005 by the American Geriatrics Society.

Item Type: Journal Article
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Journal or Publication Title: Journal of the American Geriatrics Society
Publisher: Wiley-Blackwell Publishing, Inc.
ISSN: 0002-8614
Official Date: 1 September 2005
Dates:
DateEvent
1 September 2005Published
Volume: 53
Number: 9
Page Range: pp. 1618-1622
DOI: 10.1111/j.1532-5415.2005.53455.x
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access

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