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A novel dizinc bridged hydroxamate model for hydroxamate inhibited zinc hydrolases

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UNSPECIFIED. (2002) A novel dizinc bridged hydroxamate model for hydroxamate inhibited zinc hydrolases. CHEMICAL COMMUNICATIONS (11). pp. 1210-1211. ISSN 1359-7345

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Official URL: http://dx.doi.org/10.1039/b202612k

Abstract

Reaction of Zn(OAc)(2).2H(2)O with tmen leads to the formation of [Zn(tmen)(OAc)(2)] (I) which reacts with benzohydroxamic acid to form Zn(BA)(2).H2O (II) and the novel dizinc hydroxamate bridged complex [Zn-2(mu-OAc)(2)(OAc)(2)-(mu-BA)(tmen)](III), which may also be prepared by self-assembly and whose structure closely mimics that of the native hydroxamate inhibited Aeromonas proteolytica aminopeptidase.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Journal or Publication Title: CHEMICAL COMMUNICATIONS
Publisher: ROYAL SOC CHEMISTRY
ISSN: 1359-7345
Date: 2002
Number: 11
Number of Pages: 2
Page Range: pp. 1210-1211
Identification Number: 10.1039/b202612k
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/10938

Data sourced from Thomson Reuters' Web of Knowledge

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