Skip to content Skip to navigation
University of Warwick
  • Study
  • |
  • Research
  • |
  • Business
  • |
  • Alumni
  • |
  • News
  • |
  • About

University of Warwick
Publications service & WRAP

Highlight your research

  • WRAP
    • Home
    • Search WRAP
    • Browse by Warwick Author
    • Browse WRAP by Year
    • Browse WRAP by Subject
    • Browse WRAP by Department
    • Browse WRAP by Funder
    • Browse Theses by Department
  • Publications Service
    • Home
    • Search Publications Service
    • Browse by Warwick Author
    • Browse Publications service by Year
    • Browse Publications service by Subject
    • Browse Publications service by Department
    • Browse Publications service by Funder
  • Help & Advice
University of Warwick

The Library

  • Login
  • Admin

Head growth and intelligence from birth to adulthood in very preterm and term born individuals

Tools
- Tools
+ Tools

Jaekel, Julia, Sorg, Christian, Baeuml, Josef, Bartmann, Peter and Wolke, Dieter (2019) Head growth and intelligence from birth to adulthood in very preterm and term born individuals. Journal of the International Neuropsychological Society, 25 (1). pp. 48-56. doi:10.1017/S135561771800084X

[img]
Preview
PDF
WRAP-head-growth-intelligence-birth-adulthood-very-preterm-term-born-individuals-Wolke-2018.pdf - Accepted Version - Requires a PDF viewer.

Download (825Kb) | Preview
[img]
Preview
PDF
WRAP-Supplemental_online_figures-2018.pdf - Supplemental Material - Requires a PDF viewer.

Download (284Kb) | Preview
[img]
Preview
Image (JPEG)
WRAP-figure_1.jpg - Supplemental Material

Download (625Kb) | Preview
[img]
Preview
Image (JPEG)
WRAP-figure_2.jpg - Supplemental Material

Download (640Kb) | Preview
[img]
Preview
Image (JPEG)
WRAP-figure_3.jpg - Supplemental Material

Download (622Kb) | Preview
Official URL: http://dx.doi.org/10.1017/S135561771800084X

Request Changes to record.

Abstract

Objectives: The aim of this study was to investigate the effects of infant and toddler head growth on intelligence scores from early childhood to adulthood in very preterm (<32 weeks gestational age; VP) and/or very low birth weight (<1500 g; VLBW) and term born individuals. Methods: 203 VP/VLBW and 198 term comparisons were studied from birth to adulthood as part of the prospective geographically defined Bavarian Longitudinal Study (BLS). Head circumference was assessed at birth; 5, 20 months; and 4 years of age. Intelligence was assessed with standardized tests in childhood (6 and 8 years: K-ABC) and at 26 years (Wechsler Adult Intelligence Scale, WAIS). Structural equation modeling (SEM) was used to model the effect of head growth on IQ. Results: On average, VP/VLBW had lower head circumference at birth (27.61 cm vs. 35.11 cm, mean difference 7.49, 95% confidence interval [7.09–7.90]) and lower adult intelligence scores (88.98 vs. 102.54, mean difference 13.56 [10.59–16.53]) than term born comparison individuals. Head circumference at birth (e.g., total effect β=.48; p<.001 for adult IQ) and head growth in childhood predicted intelligence development from age 6 to 26 years in both VP/VLBW and term born individuals (70% of variance in adult IQ explained by full model). Effects of gestation and birth weight on intelligence were fully mediated by head circumference and growth. Conclusions: This longitudinal investigation from birth to adulthood indicates head growth as a proxy of brain development and intelligence. Repeated early head circumference assessment adds valuable information when screening for long-term neurocognitive risk. (JINS, 2019, 25, 48#x2013;56)

Item Type: Journal Article
Subjects: R Medicine > RJ Pediatrics
Divisions: Faculty of Medicine > Warwick Medical School > Health Sciences
Faculty of Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing
Faculty of Science > Psychology
Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Premature infants -- Intelligence levels, Birth weight, Low, Head
Journal or Publication Title: Journal of the International Neuropsychological Society
Publisher: Cambridge University Press
ISSN: 1355-6177
Official Date: January 2019
Dates:
DateEvent
January 2019Published
14 November 2018Available
23 August 2018Accepted
Volume: 25
Number: 1
Page Range: pp. 48-56
DOI: 10.1017/S135561771800084X
Status: Peer Reviewed
Publication Status: Published
Publisher Statement: This article has been published in a revised form in Journal of the International Neuropsychological Society http://dx.doi.org/10.1017/S135561771800084X. This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. © The International Neuropsychological Society 2018
Access rights to Published version: Restricted or Subscription Access
Copyright Holders: Copyright © The International Neuropsychological Society 2018
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
BMBF 01ER0801Bundesministerium für Bildung und Forschunghttp://dx.doi.org/10.13039/501100002347
PKE24Bundesministerium für Bildung und Forschunghttp://dx.doi.org/10.13039/501100002347
JUG14Bundesministerium für Bildung und Forschunghttp://dx.doi.org/10.13039/501100002347
733280H2020 European Research Councilhttp://dx.doi.org/10.13039/100010663

Request changes or add full text files to a record

Repository staff actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics

twitter

Email us: wrap@warwick.ac.uk
Contact Details
About Us