Synthesis of 2,5-dihydrofurans via alkylidene carbene insertion reactions
UNSPECIFIED. (2002) Synthesis of 2,5-dihydrofurans via alkylidene carbene insertion reactions. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (7). pp. 965-981. ISSN 1472-7781Full text not available from this repository.
Official URL: http://dx.doi.org/10.1039/b111097g
The insertion reaction of alkylidene carbenes is demonstrated to be an effective method for the synthesis of 2,5-dihydrofuran ring systems. The best results have been obtained on substrates containing electron-withdrawing substituents, which appear less prone to the competing rearrangement reaction. This insight has led to the development of a new method for the synthesis of the core structure of the squalestatin-zaragozic acid natural products.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry|
|Journal or Publication Title:||JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1|
|Publisher:||ROYAL SOC CHEMISTRY|
|Number of Pages:||17|
|Page Range:||pp. 965-981|
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