The Library
The neuronal encoding of oral fat by the coefficient of sliding friction in the cerebral cortex and amygdala
Tools
Rolls, Edmund T., Mills, Tom, Norton, Abigail B., Lazidis, Aris and Norton, Ian T. (2018) The neuronal encoding of oral fat by the coefficient of sliding friction in the cerebral cortex and amygdala. Cerebral Cortex, 28 (11). pp. 4080-4089. doi:10.1093/cercor/bhy213 ISSN 1460-2199.
|
PDF
WRAP-neuronal-encoding-oral-fat-coefficient-friction-cortex-Rolls-2018.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (495Kb) | Preview |
Official URL: https://doi.org/10.1093/cercor/bhy213
Abstract
Fat in the diet contributes to the pleasant mouthfeel of many foods, but overconsumption may contribute to obesity. Here we analyze what properties of fat in the mouth are sensed, by analyzing the responses of neurons in the macaque insular taste cortex, and two areas to which it projects the orbitofrontal cortex where the pleasantness of fat is represented, and the amygdala. We discovered that the firing rate responses of these fat-responsive neurons are correlated with the coefficient of sliding friction (CSF) and not with viscosity which reflects food thickness. Other, not fat-sensitive, neurons encoded viscosity and not the CSF. Neuronal population analyses confirmed that fat-responsive neurons conveyed information about the CSF but not about viscosity. Conversely the viscosity-sensitive neuronal population conveyed information about viscosity but not about the CSF. This new understanding of the representation of oral fat in the cerebral cortex and amygdala opens the way for the systematic development of foods with the pleasant mouthfeel of fat, together with ideal nutritional content and has great potential to contribute to healthy eating and a healthy body weight.
Item Type: | Journal Article | ||||||||
---|---|---|---|---|---|---|---|---|---|
Subjects: | Q Science > QP Physiology | ||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Computer Science | ||||||||
SWORD Depositor: | Library Publications Router | ||||||||
Library of Congress Subject Headings (LCSH): | Food -- Fat content, Cerebral cortex, Amygdaloid body | ||||||||
Journal or Publication Title: | Cerebral Cortex | ||||||||
Publisher: | Oxford University Press (OUP) | ||||||||
ISSN: | 1460-2199 | ||||||||
Official Date: | 1 November 2018 | ||||||||
Dates: |
|
||||||||
Volume: | 28 | ||||||||
Number: | 11 | ||||||||
Page Range: | pp. 4080-4089 | ||||||||
DOI: | 10.1093/cercor/bhy213 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||||
Date of first compliant deposit: | 22 January 2019 | ||||||||
Date of first compliant Open Access: | 22 January 2019 | ||||||||
RIOXX Funder/Project Grant: |
|
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |
Downloads
Downloads per month over past year