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Chemical transformations on 6-aryl-3-cyano-4-methylthio-pyran-2(H)-ones: Synthetic and structural studies on novel N-phenylpyrazoles and N-phenylpyrazolylcoumarins

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UNSPECIFIED (2002) Chemical transformations on 6-aryl-3-cyano-4-methylthio-pyran-2(H)-ones: Synthetic and structural studies on novel N-phenylpyrazoles and N-phenylpyrazolylcoumarins. INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 41 (2). pp. 360-367. ISSN 0376-4699

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Abstract

Seven 6-aryl-3-cyano-4-methylthiopyran-2(H)-ones 1-7 have been prepared and used for the efficient synthesis of twelve 1,3-diaryl-5-cyanomethylpyrazoles 8-19, one 3-cyanomethyl-5-(3,4-methylenedioxyphenyl)pyrazole 22 and one 5-cyanomethyl-3-phenylisoxazole 23. Further, two 1,3-diaryl-5-cyanomethylpyrazoles 10 and 11 have been used for the preparation of three novel N-phenylpyrazolyleoumarins 24-26. Structures of 3-cyano-6-(3,4-methylenedioxyphenyl)-4-methylthiopyran-2(H)-one 7, 3-cyanomethyl-5-(3,4-methylenedioxyphenyl)pyrazole 22 and 5-cyanomethyl-3-phenylisoxazole 23 have been confirmed by their X-ray crystallographic studies.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Journal or Publication Title: INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
Publisher: NATL INST SCIENCE COMMUNICATION
ISSN: 0376-4699
Date: February 2002
Volume: 41
Number: 2
Number of Pages: 8
Page Range: pp. 360-367
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/11235

Data sourced from Thomson Reuters' Web of Knowledge

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