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Patterns, temporal trends and methodological associations in the measurement and valuation of childhood health utilities

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Kwon, Joseph, Kim, Sung Wook, Ungar, Wendy J., Tsiplova, Kate, Madan, Jason and Petrou, Stavros (2019) Patterns, temporal trends and methodological associations in the measurement and valuation of childhood health utilities. Quality of Life Research, 28 . pp. 1705-1724. doi:10.1007/s11136-019-02121-z ISSN 0962-9343. [ 🗎 Public].

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Official URL: https://doi.org/10.1007/s11136-019-02121-z

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Abstract

Purpose

To systematically assess patterns and temporal changes in the measurement and valuation of childhood health utilities and associations between methodological factors.

Methods

Studies reporting childhood health utilities using direct or indirect valuation methods, published by June 2017, were identified through PubMed, Embase, Web of Science, PsycINFO, EconLit, CINAHL, Cochrane Library, and PEDE. The following were explored: patterns in tariff application; linear trends in numbers of studies/samples and paediatric cost-utility analyses (CUAs) and associations between them; changes in proportions of studies/samples within characteristic-based categories over pre-specified periods; impact of National Institute for Health and Care Excellence (NICE) guidance on primary UK research; and associations between valuation method, age and methodological factors.

Results

335 studies with 3,974 samples covering all ICD-10 chapters, 23 valuation methods, 12 respondent types, and 42 countries were identified by systematic review. 34.0% of samples using indirect methods compatible with childhood applied childhood-derived tariffs. There was no association between numbers of studies/samples and numbers of CUAs. Compared to 1990-2008, 2009-June 2017 saw a significant fall in the proportion of studies using case series; significant compositional changes across ICD-10 chapters; and significantly higher sample proportions using childhood/adolescent-specific and adult-specific indirect valuation methods, and based on pre-adolescents, self-assessment, self-administration and experienced health states. NICE guidance was weakly effective in promoting reference methods. Associations between valuation method, age and methodological factors were significant.

Conclusion

1990-2017 witnessed significant changes in primary research on childhood health utilities. Health technology assessment agencies should note the equivocal effect of methodological guidance on primary research methods.

Item Type: Journal Article
Subjects: R Medicine > RJ Pediatrics > RJ101 Child Health. Child health services
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Children -- Health and hygiene -- Statistics -- Methodology
Journal or Publication Title: Quality of Life Research
Publisher: Springer Netherlands
ISSN: 0962-9343
Official Date: 15 July 2019
Dates:
DateEvent
15 July 2019Published
19 February 2019Available
23 January 2019Accepted
Volume: 28
Page Range: pp. 1705-1724
DOI: 10.1007/s11136-019-02121-z
Status: Peer Reviewed
Publication Status: Published
Reuse Statement (publisher, data, author rights): This is a post-peer-review, pre-copyedit version of an article published in Quality of Life Research. The final authenticated version is available online at: http://dx.doi.org/[insert DOI]”.
Access rights to Published version: Restricted or Subscription Access
Date of first compliant deposit: 29 January 2019
Date of first compliant Open Access: 4 March 2019
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
UNSPECIFIEDBirmingham Science CityUNSPECIFIED
UNSPECIFIEDAdvantage West Midlands (AWM)UNSPECIFIED
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