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Is enteral feeding tolerated during therapeutic hypothermia?
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Williams, Marie-Louise and Nolan, Jerry P. (2014) Is enteral feeding tolerated during therapeutic hypothermia? Resuscitation, 85 (11). pp. 1469-1472. doi:10.1016/j.resuscitation.2014.08.018 ISSN 0300-9572.
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Official URL: http://dx.doi.org/10.1016/j.resuscitation.2014.08....
Abstract
Objective
To determine whether patients undergoing therapeutic hypothermia following cardiac arrest tolerate early enteral nutrition.
Methods
We undertook a single-centre longitudinal cohort analysis of the tolerance of enteral feeding by 55 patients treated with therapeutic hypothermia following resuscitation from cardiac arrest. The observation period was divided into three phases: (1) 24 h at target temperature (32–34 °C); (2) 24 h rewarming to 36.5 °C; and (3) 24 h maintained at a core temperature below 37.5 °C.
Results
During period 1, patients tolerated a median of 72% (interquartile range (IQR) 68.7%; range 31.3–100%) of administered feed. During period 2 (rewarming phase), a median of 95% (IQR 66.2%; range 33.77–100%) of administered feed was tolerated. During period 3 (normothermia) a median of 100% (IQR 4.75%; range 95.25–100%) of administered feed was tolerated. The highest incidence of vomiting or regurgitation of feed (19% of patients) occurred between 24 and 48 h of therapy.
Conclusions
Patients undergoing therapeutic hypothermia following cardiac arrest may be able to tolerate a substantial proportion of their daily nutritional requirements. It is possible that routine use of prokinetic drugs during this period may increase the success of feed delivery enterally and this could usefully be explored.
| Item Type: | Journal Article | ||||||||
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| Subjects: | R Medicine > RC Internal medicine R Medicine > RM Therapeutics. Pharmacology |
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| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Cardiac arrest -- Treatment, Enteral feeding | ||||||||
| Journal or Publication Title: | Resuscitation | ||||||||
| Publisher: | Elsevier Ireland Ltd | ||||||||
| ISSN: | 0300-9572 | ||||||||
| Official Date: | November 2014 | ||||||||
| Dates: |
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| Volume: | 85 | ||||||||
| Number: | 11 | ||||||||
| Page Range: | pp. 1469-1472 | ||||||||
| DOI: | 10.1016/j.resuscitation.2014.08.018 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Access rights to Published version: | Restricted or Subscription Access | ||||||||
| Date of first compliant deposit: | 6 February 2019 | ||||||||
| Date of first compliant Open Access: | 7 February 2019 |
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