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Is enteral feeding tolerated during therapeutic hypothermia?

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Williams, Marie-Louise and Nolan, Jerry P. (2014) Is enteral feeding tolerated during therapeutic hypothermia? Resuscitation, 85 (11). pp. 1469-1472. doi:10.1016/j.resuscitation.2014.08.018 ISSN 0300-9572.

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Official URL: http://dx.doi.org/10.1016/j.resuscitation.2014.08....

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Abstract

Objective

To determine whether patients undergoing therapeutic hypothermia following cardiac arrest tolerate early enteral nutrition.

Methods

We undertook a single-centre longitudinal cohort analysis of the tolerance of enteral feeding by 55 patients treated with therapeutic hypothermia following resuscitation from cardiac arrest. The observation period was divided into three phases: (1) 24 h at target temperature (32–34 °C); (2) 24 h rewarming to 36.5 °C; and (3) 24 h maintained at a core temperature below 37.5 °C.

Results

During period 1, patients tolerated a median of 72% (interquartile range (IQR) 68.7%; range 31.3–100%) of administered feed. During period 2 (rewarming phase), a median of 95% (IQR 66.2%; range 33.77–100%) of administered feed was tolerated. During period 3 (normothermia) a median of 100% (IQR 4.75%; range 95.25–100%) of administered feed was tolerated. The highest incidence of vomiting or regurgitation of feed (19% of patients) occurred between 24 and 48 h of therapy.

Conclusions

Patients undergoing therapeutic hypothermia following cardiac arrest may be able to tolerate a substantial proportion of their daily nutritional requirements. It is possible that routine use of prokinetic drugs during this period may increase the success of feed delivery enterally and this could usefully be explored.

Item Type: Journal Article
Subjects: R Medicine > RC Internal medicine
R Medicine > RM Therapeutics. Pharmacology
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Cardiac arrest -- Treatment, Enteral feeding
Journal or Publication Title: Resuscitation
Publisher: Elsevier Ireland Ltd
ISSN: 0300-9572
Official Date: November 2014
Dates:
DateEvent
November 2014Published
2 September 2014Available
15 August 2014Accepted
Volume: 85
Number: 11
Page Range: pp. 1469-1472
DOI: 10.1016/j.resuscitation.2014.08.018
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Date of first compliant deposit: 6 February 2019
Date of first compliant Open Access: 7 February 2019

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