The Library
DNA as a catalyst and catalytic template for the racemisation of metal tris-phenanthroline complexes
Tools
Tools
Tools
Rodger, Alison, Nordén, Bengt, 1945-, Rodger, P. Mark and Bates, Paula J.. (2002) DNA as a catalyst and catalytic template for the racemisation of metal tris-phenanthroline complexes. European Journal of Inorganic Chemistry, Vol.2002 (No.1). pp. 49-53. ISSN 1434-1948
![[img]](http://wrap.warwick.ac.uk/style/images/fileicons/application_pdf.png)
|
PDF
WRAP_Rodger_0582931-ch-240811-2002._70._ejic_1_49.pdf - Submitted Version - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader Download (79Kb) |
Official URL: http://dx.doi.org/10.1002/1099-0682(20021)2002:1<4...
Abstract
[Fe(1,10-phenanthroline)(3)](2+) is known to racemise in solution and DNA is known to shift the equilibrium point of the Delta/Lambda[Fe(1,10-phenanthroline)(3)](2+) mixture from 50:50 to a position favouring a slight excess of the Delta enantiomer. In this paper it is shown that DNA catalyses the racemisation reaction, presumably by providing vibrational energy to species that bind in a less favoured mode for that enantiomer. The racemisation of [Co(1,10-phenanthroline)(3)](3+), however, is not enhanced by DNA unless [Co(1,10-phenanthroline)(3)](2+) is also added to the solution. In this case, the DNA acts as a template to facilitate the Co-II reversible arrow Co-III electron transfer. Racemisation occurs while the [Co(1,10-phenanthroline)(3)](n+) is in the labile Co-II form.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Chemistry |
| Library of Congress Subject Headings (LCSH): | Racemization, Enantiomers, DNA |
| Journal or Publication Title: | European Journal of Inorganic Chemistry |
| Publisher: | Wiley-VCH Verlag GMBH |
| ISSN: | 1434-1948 |
| Date: | January 2002 |
| Volume: | Vol.2002 |
| Number: | No.1 |
| Number of Pages: | 5 |
| Page Range: | pp. 49-53 |
| Identification Number: | 10.1002/1099-0682(20021)2002:1<49::AID-EJIC49>3.0.CO;2-8 |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Restricted or Subscription Access |
| References: | 1 Härd, T.; Nordén, B.; Biopolymers 1986, 25, 12091228 2 Härd, T.; Hiort, C.; Nordén, B.; J. Biomol. Struct. Dyn. 1987, 5, 8996 3 Rehmann, J.P.; Barton, J.K.; Biochem. 1990, 29, 17011709 4 Mudasir; Yoshioka, N.; Inoue, H.; J. Inorg. Biochem. 1999, 77, 239247 5 Hiort, C.; Nordén, B.; Rodger, A.; J. Amer. Chem. Soc. 1990, 112, 19711982 6 Haworth, I. S.; Elcock, A. H.; Freeman, J.; Rodger, A.; Richards, W. G.; J. Biomol. Struct. Dyn. 1991, 9, 2344 7 Coggan, D. Z.; Haworth, I. S.; Bates, P. J.; Robinson, A.; Rodger, A.; Inorganic Chemistry, 1999, 38, 44864497 8 Williams, A.F.; A Theoretical Approach to Inorganic Chemistry; Springer-Verlag: Heidelberg, FRG, New York, 1979 9 Johnson, B.F.G.; Rodger, A.; Inorg. Chem., 1989, 28, 10031006 10 Mason, S.F.; Peart, B.J.; J. Chem. Soc. Dalton Trans. 1973, 949955 11 Mahler, H.R.; Kline, B.; Mehrota, B. D.; J. Mol. Biol. 1964, 9, 801810 12 Lee C.S.; Inorg. Chem. 1966, 5, 13971399 13 Dollimore, L.S.; Gillard, R.D.; J. Chem. Soc. Dalton Trans. 1973, 933940 14 Ferguson, J.; Hawkins, C.J.; Kane-Maguire, A.P.; Lip. H.; Inorg. Chem. 1969, 8, 771779 15 Rodger, A.; Carey, M.; “Stopped-flow circular dichroism” in Spectrometry and spectrofluorimetry: A practical approach Gore, M. (Ed.) 2000 |
| URI: | http://wrap.warwick.ac.uk/id/eprint/11365 |
Data sourced from Thomson Reuters' Web of Knowledge
Actions (login required)
 |
View Item |
