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DNA as a catalyst and catalytic template for the racemisation of metal tris-phenanthroline complexes

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Rodger, Alison, Nordén, Bengt, Rodger, P. Mark and Bates, Paula J.. (2002) DNA as a catalyst and catalytic template for the racemisation of metal tris-phenanthroline complexes. European Journal of Inorganic Chemistry, Vol.2002 (No.1). pp. 49-53. ISSN 1434-1948

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Official URL: http://dx.doi.org/10.1002/1099-0682(20021)2002:1<4...

Abstract

[Fe(1,10-phenanthroline)(3)](2+) is known to racemise in solution and DNA is known to shift the equilibrium point of the Delta/Lambda[Fe(1,10-phenanthroline)(3)](2+) mixture from 50:50 to a position favouring a slight excess of the Delta enantiomer. In this paper it is shown that DNA catalyses the racemisation reaction, presumably by providing vibrational energy to species that bind in a less favoured mode for that enantiomer. The racemisation of [Co(1,10-phenanthroline)(3)](3+), however, is not enhanced by DNA unless [Co(1,10-phenanthroline)(3)](2+) is also added to the solution. In this case, the DNA acts as a template to facilitate the Co-II reversible arrow Co-III electron transfer. Racemisation occurs while the [Co(1,10-phenanthroline)(3)](n+) is in the labile Co-II form.

Item Type:

Journal Article

Subjects:

Q Science > QD Chemistry

Divisions:

Faculty of Science > Chemistry

Library of Congress Subject Headings (LCSH):

Racemization, Enantiomers, DNA

Journal or Publication Title:

European Journal of Inorganic Chemistry

Publisher:

Wiley-VCH Verlag GMBH

ISSN:

1434-1948

Official Date:

January 2002

Dates:

Date	Event
January 2002	Published

Volume:

Vol.2002

Number:

No.1

Number of Pages:

Page Range:

pp. 49-53

Identification Number:

10.1002/1099-0682(20021)2002:1<49::AID-EJIC49>3.0.CO;2-8

Status:

Peer Reviewed

Publication Status:

Published

Access rights to Published version:

Restricted or Subscription Access

References:

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