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The structural identifiability and parameter estimation of a multispecies model for the transmission of mastitis in dairy cows

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UNSPECIFIED (2001) The structural identifiability and parameter estimation of a multispecies model for the transmission of mastitis in dairy cows. MATHEMATICAL BIOSCIENCES, 174 (2). pp. 77-90. ISSN 0025-5564

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Abstract

A structural identifiability analysis is performed on a mathematical model for the coupled transmission of two classes of pathogen. The pathogens, classified as major and minor, are aetiological agents of mastitis in dairy cows that interact directly and via the immunological reaction in their hosts. Parameter estimates are available from experimental data for all but four of the parameters in the model. Data from a longitudinal study of infection are used to estimate these unknown parameters. A novel approach and application of structural identifiability analysis is combined in this paper with the estimation of cross-protection parameters using epidemiological data. (C) 2001 Published by Elsevier Science Inc.

Item Type: Journal Article
Subjects: Q Science > QH Natural history > QH301 Biology
Journal or Publication Title: MATHEMATICAL BIOSCIENCES
Publisher: ELSEVIER SCIENCE INC
ISSN: 0025-5564
Date: December 2001
Volume: 174
Number: 2
Number of Pages: 14
Page Range: pp. 77-90
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/11390

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