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Towards a systematic understanding of structure–function relationship of dimethylsulfoniopropionate‐catabolizing enzymes
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Chen, Yin and Schäfer, Hendrik (2019) Towards a systematic understanding of structure–function relationship of dimethylsulfoniopropionate‐catabolizing enzymes. Molecular Microbiology, 111 (6). pp. 1399-1403. doi:10.1111/mmi.14230 (In Press)
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Official URL: http://dx.doi.org/10.1111/mmi.14230
Abstract
Each year, several million tons of dimethylsulfoniopropionate (DMSP) are produced by marine phytoplankton and bacteria as an important osmolyte to regulate their cellular osmosis. Microbial breakdown of DMSP to the volatile gas dimethylsulfide (DMS) plays an important role in global biogeochemical cycles of the sulphur element between land and the sea. Understanding the enzymes involved in the transformation of DMSP and DMS holds the key to a better understanding of oceanic DMSP cycles. Recent work by Shao et al. (2019) has resolved the crystal structure of two important enzymes, DmdB and DmdC, involved in DMSP transformation through the demethylation pathway. Their work represents an important step towards a systematic understanding of the structure–function relationships of DMSP‐catabolizing enzymes in marine microbes.
| Item Type: | Journal Article | |||||||||||||||
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| Subjects: | Q Science > QP Physiology | |||||||||||||||
| Divisions: | Faculty of Science > Life Sciences (2010- ) | |||||||||||||||
| Library of Congress Subject Headings (LCSH): | Enzymes, Metabolism | |||||||||||||||
| Journal or Publication Title: | Molecular Microbiology | |||||||||||||||
| Publisher: | Wiley-Blackwell Publishing Ltd. | |||||||||||||||
| ISSN: | 0950-382X | |||||||||||||||
| Official Date: | 25 February 2019 | |||||||||||||||
| Dates: |
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| Date of first compliant deposit: | 9 April 2019 | |||||||||||||||
| Volume: | 111 | |||||||||||||||
| Number: | 6 | |||||||||||||||
| Page Range: | pp. 1399-1403 | |||||||||||||||
| DOI: | 10.1111/mmi.14230 | |||||||||||||||
| Status: | Peer Reviewed | |||||||||||||||
| Publication Status: | In Press | |||||||||||||||
| Publisher Statement: | This is the peer reviewed version of the following article: Chen, Y. and Schäfer, H. (2019), Towards a systematic understanding of structure–function relationship of dimethylsulfoniopropionate‐catabolizing enzymes. Mol Microbiol. doi:10.1111/mmi.14230, which has been published in final form at https://doi.org/10.1111/mmi.14230. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. | |||||||||||||||
| Access rights to Published version: | Open Access | |||||||||||||||
| RIOXX Funder/Project Grant: |
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