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Data for Synthesis and reduction reactions of pyridones and 5-acyl-2-methoxypyridines

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Bisset, Alexander A., Dishington, Allan, Jones, Teyrnon C., Clarkson, Guy J. and Wills, Martin (2019) Data for Synthesis and reduction reactions of pyridones and 5-acyl-2-methoxypyridines. [Dataset]

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Official URL: http://wrap.warwick.ac.uk/116584

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Abstract

The synthesis of a series of pyridones, from their 2-hydroxypyridine or 2-methoxypyridine precursors, is described, along with studies into their reductions to saturated heterocycles. A number of 5-acylpyridones were prepared and were evaluated as substrates for asymmetric transfer hydrogenation prior to conversion to saturated heterocycles. The enantioselective reduction of 5-acetyl-1-benzylpyrimidine-2,4(1H,3H)-dione is also described.

Item Type: Dataset
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Science, Engineering and Medicine > Science > Chemistry
Type of Data: Experimental data
Library of Congress Subject Headings (LCSH): Organic compounds -- Synthesis, Hydroxypyridones -- Sythesis
Publisher: University of Warwick, Department of Chemistry
Official Date: 26 March 2019
Dates:
DateEvent
26 March 2019Published
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access
Copyright Holders: University of Warwick
Description:

Supplemental information underpinning publication

Funder: Engineering and Physical Sciences Research Council (EPSRC), AstraZeneca (Firm)
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
UNSPECIFIED[EPSRC] Engineering and Physical Sciences Research Councilhttp://dx.doi.org/10.13039/501100000266
UNSPECIFIEDAstraZenecahttp://dx.doi.org/10.13039/100004325
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Contributors:
ContributionNameContributor ID
DepositorWills, Martin35981

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