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Prevalence of hypertension among patients aged 50 and older living with human immunodeficiency virus

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Dakum, Patrick, Kayode, Gbenga Ayodele, Abimiku, Alash'le, Avong, Yohanna Kambai, Okuma, James, Onyemata, Ezenwa, Ali, Taofeekat, Adekanmbi, Victor and Uthman, Olalekan A. (2019) Prevalence of hypertension among patients aged 50 and older living with human immunodeficiency virus. Medicine, 98 (15). e15024. doi:10.1097/MD.0000000000015024 ISSN 1357-3039.

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Official URL: https://doi.org/10.1097/MD.0000000000015024

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Abstract

Hypertension is one of the common medical conditions observed among patients aged 50 years and elder living with HIV (EPLWH) and to date no systematic review has estimated its global prevalence. To conduct a systematic review to estimate the global prevalence of hypertension among EPLWH. PubMed/MEDLINE, Embase, the Cochrane Library, and Global Health databases for relevant publications up till May 25, 2018. Observational studies (cohort or cross-sectional studies) that estimated the prevalence of hypertension among EPLWH. Required data were extracted independently by three reviewers and the main outcome was hypertension prevalence among EPLWH. The 24 (n = 29,987) eligible studies included were conducted in North America, Europe, Africa, and Asia. A low level bias threat to the estimated hypertension prevalence rates was observed. The global prevalence of hypertension among EPLWH was estimated at 42.0% (95% CI 29.6%-55.4%), I = 100%. The subgroup analysis showed that North America has the highest prevalence of hypertension 50.2% (95% CI 29.2% -71.2%) followed by Europe 37.8% (95% CI 30.7%-45.7%) sub-Saharan Africa 31.9% (95% CI 18.5% -49.2%) and Asia 31.0% (95% CI 26.1%-36.3%). We found the mean age of the participants explaining a considerable part of variation in hypertension prevalence. This study demonstrated that two out of five EPLWH are hypertensive. North America appears to have the highest prevalence of hypertension followed by Europe, sub-Saharan Africa (SSA) and Asia respectively. Findings from this study can be utilized to integrate hypertension management to HIV management package. (Registration number: CRD42018103069).

Item Type: Journal Article
Subjects: R Medicine > RC Internal medicine
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
SWORD Depositor: Library Publications Router
Library of Congress Subject Headings (LCSH): HIV-positive persons , Hypertension
Journal or Publication Title: Medicine
Publisher: The Medicine Publishing Company
ISSN: 1357-3039
Official Date: 1 April 2019
Dates:
DateEvent
1 April 2019Published
7 March 2019Accepted
Volume: 98
Number: 15
Article Number: e15024
DOI: 10.1097/MD.0000000000015024
Status: Peer Reviewed
Publication Status: Published
Reuse Statement (publisher, data, author rights): ** From PubMed via Jisc Publications Router
Access rights to Published version: Open Access (Creative Commons)
Date of first compliant deposit: 4 June 2019
Date of first compliant Open Access: 10 June 2019

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