The Library
Data for Site-specific conjugation of antifreeze proteins onto polymer-stabilized nanoparticles
Tools
Wilkins, Laura E., Hasan, Muhammad, Fayter, Alice E. R., Biggs, Caroline I., Walker, Marc and Gibson, Matthew I. (2019) Data for Site-specific conjugation of antifreeze proteins onto polymer-stabilized nanoparticles. [Dataset]
Other (Readme file)
Contents.rtf - Published Version Available under License Creative Commons Attribution 4.0. Download (565b) |
|
Archive (ZIP) (Data file)
Data.zip - Published Version Available under License Creative Commons Attribution 4.0. Download (2579Kb) |
Official URL: http://wrap.warwick.ac.uk/117773
Abstract
Antifreeze proteins (AFPs) have many potential applications, ranging from cryobiology to aerospace, if they can be incorporated into materials. Here, a range of engineered AFP mutants were prepared and site-specifically conjugated onto RAFT polymer-stabilized gold nanoparticles to generate new hybrid multivalent ice growth inhibitors. Only the SNAP-tagged AFPs lead to potent ‘antifreeze’ active nanomaterials with His-Tag capture resulting in no activity, showing the mode of conjugation is essential. This versatile strategy will enable the development of multivalent AFPs for translational and fundamental studies.
Item Type: | Dataset | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Subjects: | Q Science > QD Chemistry Q Science > QP Physiology |
||||||||||||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry Faculty of Science, Engineering and Medicine > Science > Physics Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
||||||||||||||||||
SWORD Depositor: | Library Publications Router | ||||||||||||||||||
Type of Data: | Tabular | ||||||||||||||||||
Library of Congress Subject Headings (LCSH): | Antifreeze proteins, Nanoparticles, Ice crystals -- Growth | ||||||||||||||||||
Journal or Publication Title: | Polymer Chemistry | ||||||||||||||||||
Publisher: | University of Warwick, Department of Chemistry | ||||||||||||||||||
ISSN: | 1759-9962 | ||||||||||||||||||
Official Date: | 5 June 2019 | ||||||||||||||||||
Dates: |
|
||||||||||||||||||
DOI: | 10.1039/c8py01719k | ||||||||||||||||||
Status: | Not Peer Reviewed | ||||||||||||||||||
Publication Status: | Published | ||||||||||||||||||
Media of Output (format): | File, .rtf .opj .xlsx .png | ||||||||||||||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||||||||||||||
Copyright Holders: | University of Warwick | ||||||||||||||||||
Description: | Background data is contained in Excel or original format. |
||||||||||||||||||
Date of first compliant deposit: | 19 February 2019 | ||||||||||||||||||
Date of first compliant Open Access: | 19 February 2019 | ||||||||||||||||||
RIOXX Funder/Project Grant: |
|
||||||||||||||||||
Related URLs: | |||||||||||||||||||
Contributors: |
|
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |
Downloads
Downloads per month over past year