Balkaya, Mustafa G., Trueman, Rebecca C., Boltze, Johannes, Corbett, Dale and Jolkkonen, Jukka (2018) Behavioral outcome measures to improve experimental stroke research. Behavioural Brain Research, 352 . pp. 161-171. doi:10.1016/j.bbr.2017.07.039 ISSN 0166-4328.

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Abstract

Functional recovery after an experimental stroke can be assessed by multiple behavioral tests, however, there is no consensus about which test to use in long-term stroke recovery studies or whether the tests are affected by stroke surgery, post-operative care or behavioral compensation due to repeated testing. This review describes the tests most commonly used to assess motor and sensorimotor function, cognition and mood in stroke animals. Although it is difficult to predict the direction of future research, it may be possible to prevent false-positive results by selecting an appropriate task or a battery of tasks. It is also expected that the upcoming stroke recovery recommendations and the improved dialogue between academy, industry and healthcare professionals will further promote translational success.

Item Type:	Journal Article
Divisions:	Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- )
Journal or Publication Title:	Behavioural Brain Research
Publisher:	Elsevier BV
ISSN:	0166-4328
Official Date:	October 2018
Dates:	Date Event October 2018 Published 29 July 2017 Available 27 July 2017 Accepted
Volume:	352
Page Range:	pp. 161-171
DOI:	10.1016/j.bbr.2017.07.039
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Related URLs:	Other Repository

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