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Singular perturbation equations for 3-d excitable media

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UNSPECIFIED (2001) Singular perturbation equations for 3-d excitable media. In: Annual Scientific Conference of the Society-for-Applied-Mathematics-and-Mechanics (GAMM 2000), APR 02-07, 2000, UNIV GOTTINGEN, GOTTINGEN, GERMANY.

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Abstract

In this paper the idea of Prandtl's boundary layer is exported to a field other than fluid dynamics. Excitable media, such as nerve fibers and heart tissue are typically modelled with a reaction-diffusion equations containing two chemical species that evolve on very different time scales. In three dimensions solutions of these equations take the form of rotating scroll waves (interfaces) ending on filaments. The ratio of the two time scales defines a natural small parameter epsilon. Exploiting the inherent smallness of epsilon, singular perturbation methods are used to derive three-dimensional equations for each of the two boundary layers : interface region (scroll) and filament region (core), and for the associated outer region. For scrolls with uniform twist about straight filaments, this matched asymptotic expansion method is also used to derive free-boundary equations not only at leading order but also at first order. Both orders are validated against full solutions of the reaction-diffusion equations. Using these two orders and with no adjustable parameters, the shape and frequency of waves are correctly predicted for most cases of physical interest.

Item Type: Conference Item (UNSPECIFIED)
Subjects: Q Science > QA Mathematics
T Technology > TJ Mechanical engineering and machinery
Journal or Publication Title: ZEITSCHRIFT FUR ANGEWANDTE MATHEMATIK UND MECHANIK
Publisher: WILEY-V C H VERLAG GMBH
ISSN: 0044-2267
Date: 2001
Volume: 81
Number: Suppl. 1
Number of Pages: 4
Page Range: S81-S84
Publication Status: Published
Title of Event: Annual Scientific Conference of the Society-for-Applied-Mathematics-and-Mechanics (GAMM 2000)
Location of Event: UNIV GOTTINGEN, GOTTINGEN, GERMANY
Date(s) of Event: APR 02-07, 2000
URI: http://wrap.warwick.ac.uk/id/eprint/12021

Data sourced from Thomson Reuters' Web of Knowledge

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