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Biotransformation of selamectin with Streptomyces lydicus SX-1298 using a novel static agar fermentation system with Reemay (R) mesh

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UNSPECIFIED (2001) Biotransformation of selamectin with Streptomyces lydicus SX-1298 using a novel static agar fermentation system with Reemay (R) mesh. JOURNAL OF ANTIBIOTICS, 54 (5). pp. 448-454. ISSN 0021-8820

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Abstract

A novel approach to biotransformation is described using a solid medium matrix and Reemay (R) mesh that gives efficient biotransformation of compounds with minimal matrices in the ensuing gum solids. Using this approach with a newly isolated biotransforming organism, Streptomyces lydicus SX1298, a series of hydroxylations and an O-demethylation is described for selamectin the first endectocide for cats and dogs.

Item Type: Journal Article
Subjects: T Technology > TP Chemical technology
Q Science > QR Microbiology > QR180 Immunology
Q Science > QR Microbiology
R Medicine > RS Pharmacy and materia medica
Journal or Publication Title: JOURNAL OF ANTIBIOTICS
Publisher: JAPAN ANTIBIOT RES ASSN
ISSN: 0021-8820
Date: May 2001
Volume: 54
Number: 5
Number of Pages: 7
Page Range: pp. 448-454
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/12140

Data sourced from Thomson Reuters' Web of Knowledge

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