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In vivo terahertz imaging to evaluate scar treatment strategies : silicone gel sheeting
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Wang, Jiarui, Sun, Qiushuo, Stantchev, Rayko I., Chiu, Tor-Wo, Ahuja, Anil T. and Pickwell-MacPherson, Emma (2019) In vivo terahertz imaging to evaluate scar treatment strategies : silicone gel sheeting. Biomedical Optics Express, 10 (7). pp. 3584-3590. doi:10.1364/BOE.10.003584 ISSN 2156-7085.
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Official URL: http://dx.doi.org/10.1364/BOE.10.003584
Abstract
Silicone gel sheeting (SGS) is widely used for scar treatment; however, studies showing its interaction with skin and efficacy of scar treatment are still lacking. THz light is non-ionizing and highly sensitive to changes in water content and thus skin hydration. In this work, we use in-vivo THz imaging to monitor how SGS affects the THz response of human skin during occlusion, and the associated THz reflectivity and refractive index changes are presented. We find that SGS effectively hydrates the skin beneath it, with minimal lateral effects beyond the sheeting. Our work demonstrates that THz imaging is able to detect the subtle hydration changes on the surface of human skin caused by SGS, and it has the potential to be used to evaluate different scar treatment strategies.
| Item Type: | Journal Article | ||||||||||||||||||
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| Subjects: | Q Science > QC Physics R Medicine > R Medicine (General) R Medicine > RC Internal medicine R Medicine > RD Surgery |
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| Divisions: | Faculty of Science, Engineering and Medicine > Science > Physics | ||||||||||||||||||
| Library of Congress Subject Headings (LCSH): | Terahertz spectroscopy, Diagnostic imaging, Silicones in surgery , Scars -- Treatment | ||||||||||||||||||
| Journal or Publication Title: | Biomedical Optics Express | ||||||||||||||||||
| Publisher: | Optical Society of America | ||||||||||||||||||
| ISSN: | 2156-7085 | ||||||||||||||||||
| Official Date: | 1 July 2019 | ||||||||||||||||||
| Dates: |
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| Volume: | 10 | ||||||||||||||||||
| Number: | 7 | ||||||||||||||||||
| Page Range: | pp. 3584-3590 | ||||||||||||||||||
| DOI: | 10.1364/BOE.10.003584 | ||||||||||||||||||
| Status: | Peer Reviewed | ||||||||||||||||||
| Publication Status: | Published | ||||||||||||||||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||||||||||||||||
| Date of first compliant deposit: | 19 September 2019 | ||||||||||||||||||
| Date of first compliant Open Access: | 19 September 2019 | ||||||||||||||||||
| RIOXX Funder/Project Grant: |
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