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Psychopathological outcomes of adolescent borderline personality disorder symptoms
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Winsper, Catherine, Wolke, Dieter, Scott, Jan, Sharp, Carla, Thompson, Andrew D. and Marwaha, Steven (2020) Psychopathological outcomes of adolescent borderline personality disorder symptoms. Australian and New Zealand Journal of Psychiatry, 54 (3). pp. 308-317. doi:10.1177/0004867419882494 ISSN 0004-8674.
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Official URL: https://doi.org/10.1177/0004867419882494
Abstract
Objective: Despite considerable morbidity and functional losses associated with adolescent Borderline Personality Disorder (BPD), little is known about psychopathological outcomes. This study examined associations between adolescent BPD symptoms and subsequent depressive, psychotic, and hypomanic symptoms.
Methods: We used data from the Avon Longitudinal Study of Parents and Children. Participants were adolescents living in the community who had data for all longitudinal outcomes (N=1758). We used logistic regression and path analysis to investigate associations between BPD (5 or more probable/definite symptoms) reported at age 11-12 years and depressive and psychotic symptoms reported at age 12 and 18, and lifetime hypomanic symptoms reported at age 22-23 years.
Results: Adolescent BPD symptoms were associated with psychotic symptoms (OR: 2.36, CI: 1.82-3.06) and diagnosis of depression at age 18 years (OR: 1.30, CI: 1.03-1.64), and hypomanic symptoms (OR: 2.89, CI: 2.40-3.48) at 22-23 years. Path analysis controlling for associations between all outcomes, indicated that BPD symptoms were independently associated with depressive symptoms (β=0.97, p<.001) at 12 years and hypomanic (β=0.58, p<.01) symptoms at 22-23 years. BPD symptoms were also associated with psychotic symptoms at age 12 years (β=0.58, p<.01), which were linked (β =0.34, p<0.01) to psychotic symptoms at age 18 years.
Conclusion: Adolescents with BPD symptoms are at future risk of psychotic and hypomanic symptoms, and a diagnosis of depression. Future risk is independent of associations between psychopathological outcomes, indicating that adolescent BPD symptoms have multifinal outcomes. Increasing awareness of BPD in early adolescence could facilitate timely secondary prevention of these symptoms subsequently helping to prevent future psychopathology.
Item Type: | Journal Article | |||||||||
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Subjects: | B Philosophy. Psychology. Religion > BF Psychology R Medicine > RC Internal medicine R Medicine > RJ Pediatrics |
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing Faculty of Science, Engineering and Medicine > Science > Psychology Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Library of Congress Subject Headings (LCSH): | Borderline personality disorder , Borderline personality disorder in adolescence , Depression in adolescence, Depression, Mental , Hypomania , Psychoses , Psychology, Pathological | |||||||||
Journal or Publication Title: | Australian and New Zealand Journal of Psychiatry | |||||||||
Publisher: | Sage Publications Ltd. | |||||||||
ISSN: | 0004-8674 | |||||||||
Official Date: | 1 March 2020 | |||||||||
Dates: |
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Volume: | 54 | |||||||||
Number: | 3 | |||||||||
Page Range: | pp. 308-317 | |||||||||
DOI: | 10.1177/0004867419882494 | |||||||||
Status: | Peer Reviewed | |||||||||
Publication Status: | Published | |||||||||
Reuse Statement (publisher, data, author rights): | Posted ahead of print. Winsper C, Wolke D, Scott J, Sharp C, Thompson A, Marwaha S. Psychopathological outcomes of adolescent borderline personality disorder symptoms. Australian & New Zealand Journal of Psychiatry. 2020;54(3):308-317. doi:10.1177/0004867419882494 Copyright © 2019 by The Royal Australian and New Zealand College of Psychiatrists. Reprinted by permission of SAGE Publications. DOI: https://journals.sagepub.com/home/anp | |||||||||
Access rights to Published version: | Restricted or Subscription Access | |||||||||
Date of first compliant deposit: | 25 September 2019 | |||||||||
Date of first compliant Open Access: | 26 September 2019 | |||||||||
RIOXX Funder/Project Grant: |
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