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Genetics and mechanics combine to guide the embryonic gut
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Panfilio, Kristen A. (2019) Genetics and mechanics combine to guide the embryonic gut. Nature, 572 (7770). pp. 446-447. doi:10.1038/d41586-019-02398-7 ISSN 0028-0836.
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Official URL: http://doi.org/10.1038/d41586-019-02398-7
Abstract
During embryonic development, generating the correct 3D body form, a process called morphogenesis, requires extensive tissue remodelling. Sheets of cells fold and alter their geometry, undergoing changes equivalent to the paper-folding intricacies of origami. In an early embryo, the cells that will form muscle tissue (termed the mesoderm) and gut tissue (the endoderm) move inwards, and the cells of the outer layer form the skin. Writing in Nature, Bailles et al.1 report a previously unknown aspect of how cells internalize, as revealed by studies of the fruit fly Drosophila melanogaster.
| Item Type: | Journal Article | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) | ||||||||
| Journal or Publication Title: | Nature | ||||||||
| Publisher: | Nature Publishing | ||||||||
| ISSN: | 0028-0836 | ||||||||
| Official Date: | 14 August 2019 | ||||||||
| Dates: |
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| Volume: | 572 | ||||||||
| Number: | 7770 | ||||||||
| Page Range: | pp. 446-447 | ||||||||
| DOI: | 10.1038/d41586-019-02398-7 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Access rights to Published version: | Restricted or Subscription Access |
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