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Glycoprotein degradation: Do sugars hold the key?

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UNSPECIFIED (2000) Glycoprotein degradation: Do sugars hold the key? CURRENT BIOLOGY, 10 (18). R674-R677. ISSN 0960-9822

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Abstract

Secretory glycoproteins that fail to fold or assemble correctly are retained in the endoplasmic reticulum and eventually degraded. Recent evidence shows that trimming of their N-linked oligosaccharide chains plays a key role in targeting glycoproteins for destruction.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Journal or Publication Title: CURRENT BIOLOGY
Publisher: CURRENT BIOLOGY LTD
ISSN: 0960-9822
Date: 21 September 2000
Volume: 10
Number: 18
Number of Pages: 4
Page Range: R674-R677
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/12893

Data sourced from Thomson Reuters' Web of Knowledge

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