A review of evidence on non-invasive prenatal diagnosis (NIPD) : tests for fetal RHD genotype
Freeman, Karoline, Osipenko, Leeza, Clay, Diane, Hyde, Julia and Szczepura, Ala (2007) A review of evidence on non-invasive prenatal diagnosis (NIPD) : tests for fetal RHD genotype. [Coventry]: University of Warwick. (Initial report).
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This report concentrates on three main areas.
First and foremost, we set the background context for RhD NIPD in prenatal care. While the methodology chapter describes how the literature review was carried out and how additional information was collected, the second chapter provides an overview of the key issues associated with pregnancy of RhD negative women. We present background information based on publications from 1997 to 2006 which describe the genetic condition and its prevalence (RhD negativity) in populations, as well as the frequency of cases of sensitisation and HDN (haemolytic disease of the newborn). We also discuss current service provision for RhD negative women in a number of European countries and look at how the NIPD test might be set within current service contexts.
|Subjects:||R Medicine > RJ Pediatrics|
|Divisions:||Faculty of Medicine > Warwick Medical School > Health Sciences > Population, Evidence & Technologies (PET) > Warwick Evidence
Faculty of Medicine > Warwick Medical School
|Library of Congress Subject Headings (LCSH):||Prenatal diagnosis, Diagnosis, Noninvasive|
|Series Name:||Initial report|
|Publisher:||University of Warwick|
|Place of Publication:||[Coventry]|
|Official Date:||January 2007|
|Number of Pages:||57|
|Status:||Not Peer Reviewed|
|Access rights to Published version:||Open Access|
Final version (published as open access)
|Funder:||Sixth Framework Programme (European Commission) (FP6)|
|Grant number:||LSHB-CT-2004-503243 (FP6)|
1. Chilcott J, Lloyd Jones M, Wight J, Forman K, Wray J, Beverley C, Tappenden P. 2003. A review of the clinical effectiveness and cost-effectiveness of routine anti-D prophylaxis for pregnant women who are rhesus-negative HTA V.7, No. 4
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