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Clinical practice guidelines of remote ischemic conditioning for the management of cerebrovascular diseases

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Ji, Xunming, Zhao, Wenbo, Boltze, Johannes, Li, Sijie, Meng, Ran, Wang, Yuan-Pang, Bix, Gregory J., Borlongan, Cesar V., Gidday, Jeffrey M., Koch, Sebastian, Quindry, John C., Ratan, Rajiv R., Veighey, Kristin, Xi, Guohua, Pignataro, Giuseppe, Hess, David C. and Hausenloy , Derek J. (2019) Clinical practice guidelines of remote ischemic conditioning for the management of cerebrovascular diseases. Conditioning Medicine, 2 (5). pp. 225-241.

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Official URL: http://www.conditionmed.org/Data/View/6390

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Abstract

Remote ischemic conditioning (RIC) using transient limb ischemia and reperfusion has been shown in small clinical studies to reduce myocardial injury and infarction in cardiac patients, although larger clinical outcome studies have been neutral. Experimental and emerging clinical studies have also reported beneficial effects of limb RIC in a number of different settings of cerebrovascular disease including stroke (ischemic and hemorrhagic), carotid artery stenosis, intracranial artery stenosis, aneurysms, small vessel disease, and vascular cognitive impairment. Although limb RIC has many advantages, in that it is non-invasive, easy to administer, relatively innocuous, cost-effective, has few or no contraindications, and may be deployed under various circumstances (e.g., home, ambulance, and hospital), several questions remain regarding its clinical application for cerebrovascular disease. Therefore, in this document, we aim to provide practicing clinicians with a coherent synthesis of the latest scientific evidence, and we propose several recommendations to help facilitate the clinical application of limb RIC for the management of cerebrovascular disease.

Item Type: Journal Article
Subjects: R Medicine > RA Public aspects of medicine
R Medicine > RC Internal medicine
Divisions: Faculty of Science > Life Sciences (2010- )
Library of Congress Subject Headings (LCSH): Cerebrovascular disease , Physician practice patterns , Cognition disorders
Journal or Publication Title: Conditioning Medicine
Official Date: October 2019
Dates:
DateEvent
October 2019Published
15 October 2019Accepted
Volume: 2
Number: 5
Page Range: pp. 225-241
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
2017YFC1308400Ministry of Science and Technologyhttp://dx.doi.org/10.13039/100007225
T2014251Changjiang Scholar Program of Chinese Ministry of Educationhttp://dx.doi.org/10.13039/501100005240
81801313 [NSFC] National Natural Science Foundation of Chinahttp://dx.doi.org/10.13039/501100001809
81620108011[NSFC] National Natural Science Foundation of Chinahttp://dx.doi.org/10.13039/501100001809
ZYLX201706Beijing Municipal Administration of Traditional Chinese Medicinehttp://dx.doi.org/10.13039/501100009600
FS/10/039/28270British Heart Foundationhttp://dx.doi.org/10.13039/501100000274
UNSPECIFIED[NIHR] National Institute for Health Researchhttp://dx.doi.org/10.13039/501100000272
UNSPECIFIEDSchool of Medicine, Duke Universityhttp://dx.doi.org/10.13039/100006512
UNSPECIFIEDNational University of Singapore.‏ ‎Faculty of Medicinehttp://viaf.org/viaf/143879397
Clinician Scientist-Senior Investigator scheme (NMRC/CSA-SI/0011/2017Ministry of Health -Singaporehttp://dx.doi.org/10.13039/501100001350
Collaborative Centre Grant scheme (NMRC/CGAug16C006Ministry of Health -Singaporehttp://dx.doi.org/10.13039/501100001350
MOE2016-T2-2-021Ministry of Education - Singaporehttp://dx.doi.org/10.13039/501100001459
EU-CARDIOPROTECTION CA16225European Cooperation in Science and Technologyhttp://dx.doi.org/10.13039/501100000921

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