Stereochemistry of the decarboxylation of glyoxylic acid by yeast pyruvate decarboxylase
UNSPECIFIED. (2000) Stereochemistry of the decarboxylation of glyoxylic acid by yeast pyruvate decarboxylase. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (15). pp. 2317-2324. ISSN 1470-4358Full text not available from this repository.
Official URL: http://dx.doi.org/10.1039/b002504f
Tritiated glyoxylic acid was incubated with pyruvate decarboxylase. The hydroxymethylthiamine diphosphate formed was ozonolysed to give tritiated glycolic acid, the absolute configuration of which was investigated by analysis using glycolate oxidase. The tritiated glycolic acid proved to be racemic. The implications of this result are discussed in relation to models for the mechanism of pyruvate decarboxylase.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry|
|Journal or Publication Title:||JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1|
|Publisher:||ROYAL SOC CHEMISTRY|
|Number of Pages:||8|
|Page Range:||pp. 2317-2324|
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