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Development of a compact, IoT-enabled electronic nose for breath analysis
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Tiele, Akira, Wicaksono, Alfian, Ayyala, Sai Kiran and Covington, James A. (2020) Development of a compact, IoT-enabled electronic nose for breath analysis. Electronics, 9 (1). 84. doi:10.3390/electronics9010084
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WRAP-development-compact-IoT-enabled-electronic-nose-breath-analysis-Covington-2020.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (1510Kb) | Preview |
Official URL: http://dx.doi.org/10.3390/electronics9010084
Abstract
In this paper, we report on an in-house developed electronic nose (E-nose) for use with breath analysis. The unit consists of an array of 10 micro-electro-mechanical systems (MEMS) metal oxide (MOX) gas sensors produced by seven manufacturers. Breath sampling of end-tidal breath is achieved using a heated sample tube, capable of monitoring sampling-related parameters, such as carbon dioxide (CO2), humidity, and temperature. A simple mobile app was developed to receive real-time data from the device, using Wi-Fi communication. The system has been tested using chemical standards and exhaled breath samples from healthy volunteers, before and after taking a peppermint capsule. Results from chemical testing indicate that we can separate chemical standards (acetone, isopropanol and 1-propanol) and different concentrations of isobutylene. The analysis of exhaled breath samples demonstrate that we can distinguish between pre- and post-consumption of peppermint capsules; area under the curve (AUC): 0.81, sensitivity: 0.83 (0.59–0.96), specificity: 0.72 (0.47–0.90), p-value: <0.001. The functionality of the developed device has been demonstrated with the testing of chemical standards and a simplified breath study using peppermint capsules. It is our intention to deploy this system in a UK hospital in an upcoming breath research study.
| Item Type: | Journal Article | ||||||
|---|---|---|---|---|---|---|---|
| Subjects: | Q Science > QC Physics Q Science > QP Physiology R Medicine > RA Public aspects of medicine T Technology > T Technology (General) T Technology > TK Electrical engineering. Electronics Nuclear engineering |
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| Divisions: | Faculty of Science, Engineering and Medicine > Engineering > Engineering | ||||||
| Library of Congress Subject Headings (LCSH): | Olfactometry -- Computer simulation, Olfactory sensors -- Computer simulation, Breath tests , Respirators (Medical equipment) , Internet of things , Embedded Internet devices | ||||||
| Journal or Publication Title: | Electronics | ||||||
| Publisher: | MDPI | ||||||
| ISSN: | 2079-9292 | ||||||
| Official Date: | 1 January 2020 | ||||||
| Dates: |
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| Volume: | 9 | ||||||
| Number: | 1 | ||||||
| Article Number: | 84 | ||||||
| DOI: | 10.3390/electronics9010084 | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Access rights to Published version: | Open Access | ||||||
| RIOXX Funder/Project Grant: |
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