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Bacterial enzymes for lignin depolymerisation : new biocatalysts for generation of renewable chemicals from biomass

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Bugg, Timothy D. H., Williamson, James J. and Rashid, Goran M. M. (2020) Bacterial enzymes for lignin depolymerisation : new biocatalysts for generation of renewable chemicals from biomass. Current Opinion in Chemical Biology, 55 . pp. 26-33. doi:10.1016/j.cbpa.2019.11.007 ISSN 1367-5931.

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Official URL: http://dx.doi.org/10.1016/j.cbpa.2019.11.007

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Abstract

The conversion of polymeric lignin from plant biomass into renewable chemicals is an important unsolved problem in the biorefinery concept. This article summarises recent developments in the discovery of bacterial enzymes for lignin degradation, our current understanding of their molecular mechanism of action, and their use to convert lignin or lignocellulose into aromatic chemicals. The review also discusses the recent developments in screening of metagenomic libraries for new biocatalysts, and the use of protein engineering to enhance lignin degradation activity.

Item Type: Journal Article
Subjects: Q Science > QK Botany
R Medicine > R Medicine (General)
T Technology > TA Engineering (General). Civil engineering (General)
T Technology > TP Chemical technology
Divisions: Faculty of Science, Engineering and Medicine > Science > Chemistry
SWORD Depositor: Library Publications Router
Library of Congress Subject Headings (LCSH): Lignin, Polymeric composites, Biosensors, Plant biomass , Lignocellulose
Journal or Publication Title: Current Opinion in Chemical Biology
Publisher: Elsevier
ISSN: 1367-5931
Official Date: April 2020
Dates:
DateEvent
April 2020Published
6 January 2020Available
19 November 2019Accepted
Volume: 55
Page Range: pp. 26-33
DOI: 10.1016/j.cbpa.2019.11.007
Status: Peer Reviewed
Publication Status: Published
Reuse Statement (publisher, data, author rights): ** Article version: AM ** Embargo end date: 06-01-2021 ** From Elsevier via Jisc Publications Router ** History: epub 06-01-2020; issue date 30-04-2020. ** Licence for AM version of this article starting on 06-01-2021: http://creativecommons.org/licenses/by-nc-nd/4.0/
Access rights to Published version: Restricted or Subscription Access
Date of first compliant deposit: 14 January 2020
Date of first compliant Open Access: 6 January 2021
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
BB/P01738X/1[BBSRC] Biotechnology and Biological Sciences Research Councilhttp://dx.doi.org/10.13039/501100000268
720303Horizon 2020 Framework Programmehttp://dx.doi.org/10.13039/100010661

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