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A key regulatory protein for flagellum length control in stable flagella
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Atkins, Madison, Týč, Jiří, Shafiq, Shahaan, Ahmed, Manu, Bertiaux, Eloïse, De Castro Neto, Artur Leonel, Sunter, Jack, Bastin, Philippe, Dean, Samuel and Vaughan, Sue (2019) A key regulatory protein for flagellum length control in stable flagella. Working Paper. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory. (Unpublished)
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Official URL: http://dx.doi.org/10.1101/872952
Abstract
Cilia and flagella are highly conserved microtubule-based organelles that have important roles in cell motility and sensing [1]. They can be highly dynamic and short lived such as primary cilia or Chlamydomonas [2] or very stable and long lived such as those in spermatozoa [3] photoreceptors [4] or the flagella of many protist cells [3,4]. Although there is a wide variation in length between cell types, there is generally a defined length for a given cell type [1]. Many unicellular flagellated and ciliated organisms have an additional challenge as they must maintain flagella/cilia at a defined length whilst also growing new flagella/cilia in the same cell. It is not currently understood how this is achieved.
| Item Type: | Working or Discussion Paper (Working Paper) | ||||
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| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Microbiology & Infection Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Journal or Publication Title: | BioRxiv | ||||
| Publisher: | Cold Spring Harbor Laboratory | ||||
| Place of Publication: | Cold Spring Harbor, New York | ||||
| Book Title: | A key regulatory protein for flagellum length control in stable flagella | ||||
| Official Date: | 11 December 2019 | ||||
| Dates: |
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| DOI: | 10.1101/872952 | ||||
| Institution: | University of Warwick | ||||
| Status: | Not Peer Reviewed | ||||
| Publication Status: | Unpublished | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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