Atkins, Madison, Týč, Jiří, Shafiq, Shahaan, Ahmed, Manu, Bertiaux, Eloïse, De Castro Neto, Artur Leonel, Sunter, Jack, Bastin, Philippe, Dean, Samuel and Vaughan, Sue (2019) A key regulatory protein for flagellum length control in stable flagella. Working Paper. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory. (Unpublished)

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Abstract

Cilia and flagella are highly conserved microtubule-based organelles that have important roles in cell motility and sensing [1]. They can be highly dynamic and short lived such as primary cilia or Chlamydomonas [2] or very stable and long lived such as those in spermatozoa [3] photoreceptors [4] or the flagella of many protist cells [3,4]. Although there is a wide variation in length between cell types, there is generally a defined length for a given cell type [1]. Many unicellular flagellated and ciliated organisms have an additional challenge as they must maintain flagella/cilia at a defined length whilst also growing new flagella/cilia in the same cell. It is not currently understood how this is achieved.

Item Type:	Working or Discussion Paper (Working Paper)
Divisions:	Faculty of Medicine > Warwick Medical School > Biomedical Sciences Faculty of Medicine > Warwick Medical School > Biomedical Sciences > Microbiology & Infection Faculty of Medicine > Warwick Medical School
Journal or Publication Title:	BioRxiv
Publisher:	Cold Spring Harbor Laboratory
Place of Publication:	Cold Spring Harbor, New York
Book Title:	A key regulatory protein for flagellum length control in stable flagella
Official Date:	11 December 2019
Dates:	Date Event 11 December 2019 Available
DOI:	10.1101/872952
Institution:	University of Warwick
Status:	Not Peer Reviewed
Publication Status:	Unpublished
Access rights to Published version:	Restricted or Subscription Access

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