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Social avoidance emerges in infancy and persists into adulthood in Fragile X syndrome

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Roberts, Jane, Crawford, Hayley, Hogan, Abigail L., Fairchild, Amanda, Tonnsen, Bridgette, Brewe, Alexis, O’Connor, Shannon, Roberts, Douglas A. and Abbeduto, Leonard (2019) Social avoidance emerges in infancy and persists into adulthood in Fragile X syndrome. Journal of Autism and Developmental Disorders, 49 (9). pp. 3753-3766. doi:10.1007/s10803-019-04051-8 ISSN 0162-3257.

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Official URL: http://dx.doi.org/10.1007/s10803-019-04051-8

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Abstract

Fragile X syndrome (FXS) is characterized by both social approach and social avoidance. However, the age of emergence and developmental trajectory of social avoidance has not been examined. This study investigates the longitudinal developmental trajectory and dynamic nature of social avoidance in males with FXS from infancy through young adulthood (n = 191). Multiple facets of social avoidance were collected using the Social Avoidance Scale (Roberts et al. 2007, 2009). Overall, 81% of males with FXS displayed social avoidance, which emerged during infancy, increased in severity across childhood, and stabilized through adolescence and early adulthood. An exaggerated “warm up” effect was also observed in FXS. This study delineates the complex profile of social avoidance, a common and impairing behavioral feature of FXS.

Item Type: Journal Article
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Journal or Publication Title: Journal of Autism and Developmental Disorders
Publisher: Springer
ISSN: 0162-3257
Official Date: 15 September 2019
Dates:
DateEvent
15 September 2019Published
4 June 2019Available
Volume: 49
Number: 9
Page Range: pp. 3753-3766
DOI: 10.1007/s10803-019-04051-8
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
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