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Existing and emerging molecular targets for the pharmacotherapy of obesity
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Glykofrydi, Spyridoula, Kokkinos, Alexander, Barber, Thomas M., Mastorakos, George and Valsamakis, Georgios (2020) Existing and emerging molecular targets for the pharmacotherapy of obesity. [Online]. (https://www.ncbi.nlm.nih.gov/books/NBK279143/#top). South Dartmouth (MA): Endotext [Internet].
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Official URL: https://www.ncbi.nlm.nih.gov/books/NBK279143/#top
Abstract
Obesity is pandemic and a multidisciplinary approach is critical for its management. Anti-obesity treatment includes lifestyle modifications combined with anti-obesity medications. Anti-obesity drugs target either central nervous system pathways, which regulate sensations of satiety and fullness, or peripheral modulators of digestion, metabolism and lipogenesis. Combined anti-obesity agents is a novel, promising field, especially the co-administration of gut hormone analogues with centrally acting molecules. Consequently, it is hoped that in the near future, individualized pharmacological management of obesity could be meaningfully achieved by targeting different pathways governing energy homeostasis and weight regulation. This chapter reviews potential molecular targets of the energy homeostasis system along with new anti-obesity drugs currently under investigation. For complete coverage of all related areas of Endocrinology, please visit our on-line FREE web-text, WWW.ENDOTEXT.ORG.
| Item Type: | Digital Scholarly Resource | ||||
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| Divisions: | Faculty of Medicine > Warwick Medical School > Biomedical Sciences Faculty of Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine Faculty of Medicine > Warwick Medical School |
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| Publisher: | Endotext [Internet] | ||||
| Place of Publication: | South Dartmouth (MA) | ||||
| Official Date: | 9 January 2020 | ||||
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| Publication Status: | Published | ||||
| Media of Output: | Digital resourse | ||||
| Access rights to Published version: | Restricted or Subscription Access | ||||
| Copyright Holders: | Copyright © 2000-2020, MDText.com, Inc. | ||||
| Description: | Feingold KR, Anawalt B, Boyce A, et al., editors |
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