(2020) Gene content evolution in the arthropods. Genome Biology, 21 (1). 15. doi:10.1186/s13059-019-1925-7 ISSN 1474-7596.
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Abstract
Arthropods comprise the largest and most diverse phylum on Earth and play vital roles in nearly every ecosystem. Their diversity stems in part from variations on a conserved body plan, resulting from and recorded in adaptive changes in the genome. Dissection of the genomic record of sequence change enables broad questions regarding genome evolution to be addressed, even across hyper-diverse taxa within arthropods. Using 76 whole genome sequences representing 21 orders spanning more than 500 million years of arthropod evolution, we document changes in gene and protein domain content and provide temporal and phylogenetic context for interpreting these innovations. We identify many novel gene families that arose early in the evolution of arthropods and during the diversification of insects into modern orders. We reveal unexpected variation in patterns of DNA methylation across arthropods and examples of gene family and protein domain evolution coincident with the appearance of notable phenotypic and physiological adaptations such as flight, metamorphosis, sociality, and chemoperception. These analyses demonstrate how large-scale comparative genomics can provide broad new insights into the genotype to phenotype map and generate testable hypotheses about the evolution of animal diversity.
Item Type: | Journal Article |
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Subjects: | Q Science > QL Zoology |
Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) |
SWORD Depositor: | Library Publications Router |
Library of Congress Subject Headings (LCSH): | Arthropoda, Genomics, DNA -- Methylation |
Journal or Publication Title: | Genome Biology |
Publisher: | BioMed Central Ltd. |
ISSN: | 1474-7596 |
Official Date: | 23 January 2020 |
Dates: | Date Event 23 January 2020 Published 26 December 2019 Accepted |
Volume: | 21 |
Number: | 1 |
Article Number: | 15 |
DOI: | 10.1186/s13059-019-1925-7 |
Status: | Peer Reviewed |
Publication Status: | Published |
Re-use Statement: | ** From PubMed via Jisc Publications Router ** History: received 06-11-2019; accepted 26-12-2019. |
Access rights to Published version: | Open Access (Creative Commons open licence) |
Date of first compliant deposit: | 12 February 2020 |
Date of first compliant Open Access: | 12 February 2020 |
RIOXX Funder/Project Grant: | Project/Grant ID RIOXX Funder Name Funder ID PP00P3_170664 Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 31003A_143936 Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung UNSPECIFIED Leibniz Graduate School on Genomic Biodiversity Research (GBR) UNSPECIFIED |
URI: | https://wrap.warwick.ac.uk/132923/ |
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